摘要
目的 分析１９９８、１９９９年１～２月临床分离的２００株革兰阴性杆菌的耐药性。方法 用Ｅ试验检测１３种抗生素对２００株革兰阴性杆菌的最低抑菌浓度（ＭＩＣ）。结果 伊米配能（ＩＰ）、头孢他啶（ＴＺ）、庆大霉素（ＧＭ）、头孢曲松（ＴＸ）、阿米卡星（ＡＫ）、头孢哌酮（ＣＰ）、头孢噻肟（ＣＴ）、头孢呋肟（ＸＭ）对肠杆菌科细菌的抗菌效果优于非发酵菌。用Ｅ试验方法检出１５株产超广谱β－内酰胺酶菌株（ＥＳＢＬｓ）。结论 Ｅ试验检测ＭＩＣ可用于细菌耐药性监测、分析以及ＥＳＢＬｓ的筛选、检测。
Objective To analyse the resistance retes of 200 gram-negative bacteria (GNB) strains from clinical isolates in 1998 and 1999. Methods The E test was used to detect the MIC of 13 antibiotics in 200 GNB strains. Results The anibiotic effects of imipenem(IP), ceftazidime (TZ), gentamicin (GM), ceftriaxone (TX), amikacin (AK), cefoperazone (CP), cefotaxime (CT), cefuro- xime (XM) on enterobacteriaceae were better than nonfermentative gram - negative bacteria. Fifteen strains producing extended spectrum β - lactamases (ESBLs) had been detected by the E test. Conclusion The E test can be used to detect and analyse the resistance of bacteria, screen and detect ESBLs.
出处
《上海第二医科大学学报》
CSCD
2001年第3期257-258,共2页
Acta Universitatis Medicinalis Secondae Shanghai
