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复方过氧乙酸溶液杀灭微生物效果的实验观察 被引量:15

EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY OF COMPOUND PERACETIC ACID SOLUTION
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摘要 复方过氧乙酸溶液(STERIS20D消毒剂)系由30%乙酸水杨酸与30%一水过硼酸钠水解化合生成过氧乙酸与过氧化氢,与40%抗腐蚀缓冲剂混合而成。为了解其杀灭微生物效果,进行了悬液与载体定量杀菌试验。结果,在 25℃ ,以其含 392.30 mg/L过氧乙酸、2333.70 mg/L过氧化氢的溶液对悬液中大肠杆菌、金黄色葡萄球菌作用1min,以其含117882mg/L过氧乙酸、7726.07mg/L过氧化氢的溶液对悬液中枯草杆菌黑色变种芽胞作用40min,杀灭率均达100%。在50-55℃,以其含1178.82mg/L过氧乙酸、7726.07mg/L过氧化氢的溶液作用30min,可将玻璃片表面HBsAg抗原性破坏。杀菌作用因有机物存在而减弱,随温度升高而增强。 The compound peracetic acid solution(STERIS 20D Disinfectant) was prepared by mixing peracetic acid, which was produced by hydrolytic combination of 30% acetylsalicylic acid and 30% sodium perborate monohydrate, with hydrogen peroxide and 40% anticorrosive buffer. In order to know its germicidal efficacy, suspension and carrier quantitative bactericidal tests were carried out. The results showed that at 25℃ its solution containing peracetic acid 392.30 mg / L and hydrogen peroxide 2333.70 mg / L with a l min contact time could kill 100% of Escherichia coli and Staphylococcus aureus in suspension and its solution containing peracetic acid 1178.82 mg / L and hydrogen peroxide 7726.07 mg / L with a 40 min contact time could kill 100% of spores of Bacillus subtilis var. niger in suspension. At 50 - 55℃, its solution containing peracetic acid 1 178.82 mg / L and hydrogen peroxide 7726.07 mg / L with a 30 min contact time could destroy the antigenicity of HBsAg on surface of glass slide. Its germicidal efficacy decreased due to presence of organic substance and increased with increasing temperature.
出处 《中国消毒学杂志》 CAS 2001年第1期6-10,共5页 Chinese Journal of Disinfection
关键词 过氧乙酸复方消毒剂 杀芽胞作用 HBSAG 枯草杆菌黑色变种 大肠杆菌 金黄色葡萄球菌 腐蚀性 compound peracetic acid disinfectant sporicidal effect HBsAg Bacillus subtilis var. niger Escherichia coli Staphylococcus aureus corrosiveness
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