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“醒脑开窍”针法对大脑中动脉阻断后局灶性脑缺血大鼠神经细胞功能的影响 被引量:19

The effect of xingnao kaiqiao acupuncture on nerve cells after focal brain ischemia induced by middle cerebral artery occulusion.
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摘要 目的探讨“醒脑开窍”针刺法治疗脑梗死的机理。方法以热凝法阻断大鼠一侧大脑中动脉 (MCAo)造成局灶性脑缺血为实验模型,用免疫组化法观察缺血区脑组织 c- fos蛋白的动态化及针刺的干预作用。结果针刺能增强各时段 c- fos蛋白的表达,提高神经细胞的应激能力和对脑缺血损伤产生适应性变化,增强脑组织的修复能力,且醒脑组优于常规组。结论“醒脑开窍”针法作用优于常规针刺法。 Objective TO study the mechanism of xingnao kaiqiao acupuncture for brain occlusion.Method using one- side middle cerebral artery occlusion (MCAo)rats by thermoregulation as focal cerebral ischemis experimental animal.The dynamic changes of c- fos protein in sichemic region of brain tissue were observed by immunohistochemitry method.Meanwhile the effect of acupuncture was studied.Result The outcome of xingnao kaiqiao group was better than that of routine group.Acupuncture could enhance the expression of c- fos protein in all stages of ischemia,promote the stress ability of neuron produce adaptive changes to brain sichemia and improve recovery of brain tissue.Conclusion The dffect of xingnao kaiqiao acupuncture was better than that of routine acupuncture.
出处 《现代康复》 CSCD 2001年第3期53-53,65,共2页 Modern Rehabilitation
关键词 “醒脑开窍”针刺法 大脑中动态阻断 C-FOS蛋白 局灶性脑缺血 大鼠 神经细胞 xingnao kaiqiao acupuncture middle cerebral artery occlusion(MCAo) c- fos protein
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