摘要
目的检测孕期、手术前及输血前血清感染性标志物,为感染性疾病的筛查提供参考依据。方法对入住医院的500例孕妇、待手术及输血患者空腹抽取肘静脉血,对乙型肝炎五项、丙型肝炎抗体(抗-HCV)、梅毒(抗-TP)及抗-HIV感染性指标进行检测,并分析感染率;数据采用SPSS17.0数据包进行处理。结果 500例患者中HBV感染66例占13.20%、抗-HCV 9例占1.80%、抗-TP 4例占0.80%、抗-HIV 1例占0.20%;O血型患者出现感染性指标阳性的风险比较高,为23.2%,其次AB血型为18.9%、A血型为14.5%、B血型患者发生风险最小为11.7%;不同血型之间患者输血前HBV阳性、抗-HCV阳性、抗-TP阳性及抗-HIV阳性差异比较发现,AB血型患者梅毒感染的风险明显低于O血型患者,比较差异有统计学意义(P<0.05),其余感染指标比较差异无统计学意义;80例感染患者中HBV感染联合抗-HCV阳性发生率最高为7.5%。结论孕期与手术前及输血前对血清感染性标志物,乙型肝炎五项标志物、抗-HCV、抗-TP、抗-HIV进行检测可以更好的了解患者感染情况,以便医护人员在日常治疗及手术过程中更好的自我保护,同时为明确血清感染性疾病提供依据。
OBJECTIVE To analyze the markers related to infectious diseases during pregnancy,before surgery and blood transfusion and understand the incidence of infections so as to provide reliable basis for screening of infectious diseases.METHODS A total of 500pregnant women who needed the surgery and blood transfusion were enrolled in the study,then the fasting cubital fossa vein blood samples were collected,the five hepatitis B indicators,hepatitis C antibody（anti-HCV）,syphilis（TP）resistance,and anti-HIV infective indexes were detected,the incidence of infections was analyzed,and the statistical analysis of data was performed with the use of SPSS17.0software.RESULTS Among the 500patients,the HBV infection occurred in 66cases（13.20%）,the anti-HCV in9（1.80%）cases,the anti-TP in 4（0.80%）cases,the anti-HIV in 1（0.20%）case.The patients with type O blood were at high risk of positive infective indicator,accounting for 23.2%,followed by the patients with the type AB blood（18.9%）,the patients with type A blood（14.5%）,and the patients with type B blood（11.7%）.As compared with the positive HBV,positive anti-HCV,positive anti-TP,and positive anti-HIV of the patients with different types of blood before the blood transfusion,the risk of syphilis infection was significantly lower in the patients with blood type AB than in the patients with blood type O,the difference was significant（P〈0.05）,the differences in other infective indicators were not significant.Among the 80patients with infections,the incidence of HBV infection combined with positive anti-HCV was the highest（7.5%）.CONCLUSIONThe detection of the five hepatitis B indicators,anti-HCV,anti-TP,and anti-HIV during the pregnancy and before surgery and blood transfusion may contribute to the understanding of the prevalence of infections in the patients and the selfprotection of the health care workers during the daily treatment and surgery and define the serological infectious diseases.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第14期3635-3637,共3页
Chinese Journal of Nosocomiology
基金
河南科技厅重点基金项目(20120517RZ)
关键词
输血
手术
孕期
乙型肝炎
丙型肝炎
Blood transfusion
Surgery
Pregnancy
Hepatitis B
Hepatitis C
