摘要
注意力缺陷多动障碍病因复杂,发病机制至今未明,中医药因整体观念和辨证论治已突显其治疗优势,在动物实验基础研究方面也取得一定的成果。文章检索了近10年相关文献,从动物模型选择、行为学实验、神经递质调节等方面探讨注意力缺陷多动障碍的中医药动物实验研究现况及存在问题。目前动物实验模型多选用自发性高血压大鼠,不能体现中医特色,实验研究低水平重复,缺乏高层次的系统研究。
The pathogenesis of ADHD has been unknown so far because of its complexity. Based on the theory of holism concept and syndrome differentiation and treatment, Chinese medicine has proved its therapeutic advantages and achievements in terms of basic animal experiment research. The article searches the relevant literature in recent 10 years, and then discusses and analyses the experimental research progress in terms of animal models, animal behavior, and neurotransmitters, etc. It's found that SHR is the most popular animal model without reflecting TCM characteristic, most of which are low-level repetition studies rather than high-level system researches.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2014年第6期1937-1939,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金(No.81273801)
教育部高等学校博士学科点专项科研基金(No.20123237110002)
江苏省普通高校研究生科研创新计划项目(No.CXZZ12_0613)~~