摘要
目的:观察辨证论治慢性心力衰竭的临床疗效。方法:将180例患者随机分为3组,每组60例,3组患者均给予西医常规治疗。气虚血瘀组加用保元汤合补阳还五汤加减治疗,阳虚水泛组加用真武汤加味治疗。比较3组临床疗效及左室射血分数(LVEF)、左室短轴缩短率(FS)、肿瘤坏死因子(TNF-α)、血管紧张素Ⅱ(Ang-Ⅱ)、白细胞介素-6(IL-6)等指标的变化。结果:气虚血瘀组、阳虚水泛组总有效率均高于对照组(P<0.05);LVEF、FS3组治疗后均较治疗前有明显提高(P<0.05),气虚血瘀组、阳虚水泛组与对照组相比,差异具有统计学意义(P<0.05);3组治疗后Ang-Ⅱ、IL-6及TNF-α显著降低(P<0.05)。结论:辨证论治疗慢性心力衰竭临床疗效显著。
Objective： To observe therapeutic effects of syndrome differentiation and treatment in treating chronic heart failure（CHF）. Methods：All 180 patients were randomly divided into three groups, 60 cases each group, all the patients received conventional therapy of western medicine. Qi-insufficiency blood-stasis group took BaoYuan Tang and modified BuYang HuanWu Tang, Yang-deficiency water-flooding group received modified ZhenWu Tang. The changes of LVEF, FS, TNF-α, Ang-Ⅱand IL-6 of three groups were compared as well as therapeutic effects. Results：Total effective rates of Qi-insufficiency blood-stasis group and Yang-deficiency water-flooding group were higher than that of the control group （P〈0.05）;LVEF and FS of three groups after treating were improved signifi-cantly compared with before treating （P〈0.05）, the differences had statistical meaning when Qi-insufficiency blood-stasis group and Yang-deficiency water-flooding group were compared with the control group （P〈0.05）;Ang-Ⅱ, IL-6 and TNF-αof three groups after treating were decreased （P〈0.05）. Conclusion：Treating CHF by syndrome differentiation and treatment is effective.
出处
《西部中医药》
2014年第6期78-79,共2页
Western Journal of Traditional Chinese Medicine
关键词
心力衰竭
慢性
辨证论治
安全性
heart failure,chronic
syndrome differentiation and patterns
the safety
