摘要
目的:牛痘疫苗接种家兔炎症皮肤提取物(神经妥乐平)注射液联合α-硫辛酸治疗痛性糖尿病神经病变的临床疗效。方法:将176例痛性2型糖尿病神经病变患者随机分为对照组(91例)和治疗组(85例)。对照组患者使用α-硫辛酸450 mg,每日一次,共4周。治疗组在此基础上使用神经妥乐平7.2 NU,每日一次,共4周。观察两组治疗前后的神经传导速度和疼痛评分情况。结果:治疗组患者和对照组患者的周围神经传导速度与治疗前比较,均有明显增加,并且治疗组患者的效果要明显优于对照组,两组比较差异明显(P<0.05)。治疗组及对照组患者疼痛评分均有改善,且治疗组效果优于对照组。结论:牛痘疫苗接种家兔炎症皮肤提取物注射液联合α-硫辛酸具有协同作用,可提高痛性2型糖尿病神经病变的疗效。
Objective：To explore the effectiveness of Neurotropin combined with α-lipoic acid for the treatment of diabetic peripheral neuropathy （DPN）.Methods：176 patients with DPN were randomly assigned into two groups.In control group 91 cases were given α-lipoic acid,whereas in treated group 85 cases were received Neurotropin and α-lipoic acid for 4 weeks.The visual analogue scale （VAS） and nerve conduction velocity between two groups were compared before and after treatment Results：EMG showed that the nerve conduction velocity after 4 weeks of treatment in the two groups were higher than before treatment （P 〈 0.05）,and the nerve conduction velocity after treatment in the treated group was improved more than the control group.Posttreatment VAS in the two groups were both higher than before,and VAS in the treated group was superior to that in the control group.Conclusion：The union treatment of Neurotropin and α-lipoic acid had better effects on DPN.
出处
《中国疼痛医学杂志》
CAS
CSCD
北大核心
2014年第6期421-423,共3页
Chinese Journal of Pain Medicine
