摘要
目的探讨接受颈动脉介入治疗的严重颈动脉狭窄(carotid artery stenosis,CAS)患者术前行冠状动脉(冠脉)造影(coronary angiography,CAG)的意义。方法连续入选2002年6月至2013年10月之间197例行颈动脉介入治疗的严重CAS患者,所有患者在行颈动脉介入治疗前常规进行CAG。据造影结果分析CAS和冠状动脉疾病(coronary artery disease,CAD)的关系。结果 CAS合并CAD共155例,共患率为78.68%。不同CAS病变血管数不同冠脉狭窄程度的患者比例比较,差异无统计学意义(χ2=6.812,P=0.078)。不同CAS病变血管数不同冠脉病变血管数的患者比例比较,差异有统计学意义(χ2=11.726,P=0.008)。以分类变量CAS有无合并CAD为因变量进行多元回归的Logistic回归分析,未发现在CAS患者中发生CAD的独立危险因素。线性回归分析显示,CAS病变血管数与冠脉病变血管数正相关(r=0.328,P=0.030)。结论 CAS与CAD的共患率较高,颈动脉病变血管数与冠脉病变血管数存在正相关,这对患者的整体治疗策略有重要指导意义。
Objectives To explore the significance of coronary angiography before interventional therapy in patients with severe carotid artery stenosis（CAS）. Methods This study included 197 consecutive patients with CAS who were receiving interventional therapy during June 2002 to October 2013. Coronary angiography was performed on all the patients before routine treatment. According to the angiographic results, the relationship between CAS and coronary artery disease （CAD） was analyzed. Results There were 155 out of 197 patients suffered from CAS complicated with CAD, and the co-morbidity rate was 78.68%. There was no significant difference in ratio of patients with different numbers of vessel disease （NVD） of CAS and different degrees of CAD （χ2=6.812,P=0.078）. The difference of ratio of patients with different NVD of CAS and different NVD of CAD was significant（χ2=11.726,P=0.008）. Based on whether CAS combined CAD as an element,a Logistic returning analysis was made, but the risk factor of CAD occurring in patients with CAS was not found. NVD of CAS positively correlated with NVD of CAD（r=0.328,P=0.030）. Conclusions The co-morbidity rate of sever CAS and CAD is high. There is a relationship between NVD of CAS and NVD of CAD, which is meaningful for guiding therapy.
出处
《岭南心血管病杂志》
2014年第3期342-346,共5页
South China Journal of Cardiovascular Diseases
关键词
颈动脉狭窄
冠状动脉疾病
冠状动脉造影
carotid artery stenosis
coronary artery disease
coronary angiography
