摘要
目的:探讨便通胶囊联合莫沙必利治疗老年痔患者术后便秘患者的临床疗效,为临床治疗老年痔患者术后便秘提供参考.方法:收集河南省南阳市中心医院肛肠科收治的78例老年痔术后便秘患者,随机分为观察组和对照组,各39例,观察组采用便通胶囊+莫沙必利治疗,对照组采用莫沙必利治疗,比较两组患者临床治疗效果.观察组2例大便不成形,坚持服用药物治疗后患者的临床症状缓解;对照组6例腹痛胀,经过排便灌肠之后缓解.两组的对象均无肝肾功能异常的情况.结果:观察组患者治疗痊愈26例(66.7%),显效7例(17.9%),有效4例(10.3%),无效2例(5.1%),总有效率94.9%;对照组患者痊愈17例(43.6%),显效4例(10.3%),有效10例(25.9%),无效8例(20.5%),总有效率为79.5%,差异具有统计学意义(P<0.05).结论:通便胶囊具有健脾益肾、润肠通便的作用,莫沙必利能促进胃肠蠕动,将两者联合用于治疗老年痔术后便秘取得良好的效果,值得临床推广应用.
AIM： To assess the curative effect of Biantong capsules combined with mosapride in the treat- ment of constipation in elderly patients after hemorrhoid surgery. METHODS： Seventy-eight elderly patients with constipation who had undergone hemorrhoid surgery at Nanyang Central Hospital were randomly divided into either an observation group or a control group （n = 39 for each）. The observation group was treated with Biantong capsules plus mosapride, and the control group was treated with mosapride alone. The curative effect was compared between the two groups. RESULTS： Two patients in the observation group developed loose stool, which was re-lieved after continued treatment. Six patients in the control group developed abdominal pain, which was resolved after enema administration. No liver function abnormalities were observed in either group. In the observation group, 26 （66.7%） cases were cured, 7 （17.9%） cases showed a significant response, 4 （10.3%） cases showed a partial response, and 2 （5.1%） cases showed no response; the corresponding figures in the control group were 17 （43.6%）, 4 （10.3%）, 10 （25.9%） and 8 （20.5%）, respectively. The total response rate was significantly higher in the treatment group than in the control group （94.9% vs 79.5%, P 〈 0.05）. CONCLUSION： Biantong capsules combined with mosapride has a good curative effect in the treatment of constipation in elderly patients after hemorrhoid surgery.
出处
《世界华人消化杂志》
CAS
北大核心
2014年第15期2213-2216,共4页
World Chinese Journal of Digestology
关键词
便通胶囊
莫沙必利
便秘
痔
Biantong capsules
Mosapride
Constipation
Hemorrhoids
