摘要
目的:观察喜炎平注射液联合开喉剑喷雾剂(儿童型)治疗小儿疱疹性咽峡炎的临床疗效。方法:132例临床诊断为疱疹性咽峡炎的患儿按随机表法分为2组,治疗组67例,采用喜炎平注射液联合开喉剑喷雾剂治疗;对照组65例,采用注射用更昔洛韦治疗;疗程为5 d。对2组疗效进行比较分析。结果:治疗组总有效率为91%,对照组总有效率为77%,2组比较差异有统计学意义(P<0.05)。治疗组发热消退时间、拒食流涎消退时间、疱疹消退时间分别为(2.5±0.8),(2.5±0.9),(3.2±1.0)d,对照组分别为(3.1±0.9),(3.8±1.5),(5.1±1.3)d,2组之间差异均有统计学意义(P<0.01)。结论:喜炎平注射液联合开喉剑喷雾剂(儿童型)治疗小儿疱疹性咽峡炎,能较快改善患儿临床症状及体征,治疗疗程短、疗效明显,无明显毒副作用,值得推广应用。
OBJECTIVE To observe the effect of Xiyanping injection combined with Kaihoujian spray （children） in treating herpangina in children.METHODS 132 cases of herpetic angina patients which met the inclusion criteria and attended the study voluntarily were randomly divided into the treatment group （TG） and the control group （CG）. 67 cases of patients in TG were treated with Xiyanping injection combined with Kaihoujian spray; 65 cases of patients in CG were treated with ganciclovir injec- tion. The course of treatment was 5 d. The curative effects were compared between the two groups. RESULTS The total ef- fective rate in TG （91 %） was higher than that in CG（77%） （P〈0. 05） . The duration of the subsiding fever, anti-feeding/sal- ivation and the disappearing herpes were（2. 5 ± 0. 8）, （2. 5 ± 0. 9）, （3.2 ± 1.0） d in TG, were（3.1 ± 0. 9）, （3. 8 ± 1.5）, （5.1± 1.3） d in CG respectively. The differences were statistically significant （P〈0. 01 ）. CONCLUSION Xiyanping injection com- bined with Kaihoujian spray （children） which could improve the clinical symptoms and signs, shorten the course of treatment had obvious curative effect and without significant side effects in treating herpangina in children. Xiyanping injection combined with Kaihoujian spray （child） is worthy of popularization and application.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2014年第11期923-926,共4页
Chinese Journal of Hospital Pharmacy
