摘要
目的 通过高分辨力超声 ,观测临界高血压患者血管内皮功能是否受到损伤。方法 对照组及临界高血压患者各 10例 ,通过反应性充血后肱动脉内径变化评估血管内皮功能。结果 与对照组相比 ,临界高血压患者内皮依赖性舒张功能明显受损 (5 .49± 3.78vs 10 .11± 2 .70 ,P <0 .0 5 ) ,而内皮非依赖性舒张功能无明显变化 (14.86± 4.73vs 18.36± 2 .39,P >0 .0 5 ) ,其内皮依赖性舒张功能与年龄、血糖、血脂之间无明显的相关性。
Objective To evaluate the endothelial dysfunction by the high resolution ultrasound in borderline hypertension patients. Methods In 10 borderline hypertension patients and 10 control subjects,the endothelial function was evaluated by the high resolution ultrasound through the diameter change in brachial artery after reactive hyperemia. Results The endothelium depended dilatation was destroyed significantly in borderline hypertension patients than control subjects(5.49±3.78 vs 10.11±2.70 P <0.05),but there was no difference in endothelium independed dilatation(14.86±4.73 vs 18.36±2.39, P >0.05). The significant relations between endothelium depended dilatation and blood surge, total cholesterol, HDL were not found. Conclusion High resolution ultrasound could measured endothelial dysfunction in the early stage of hypertension. [
出处
《中国医学影像技术》
CSCD
2001年第2期157-158,共2页
Chinese Journal of Medical Imaging Technology
