摘要
目的研究持续无创正压通气(NCPAP)对阻塞性睡眠呼吸暂停综合症(OSAHS)患者的血压和血脂代谢的影响。方法选择52例OSAHS患者作为观察组,采用NCPAP治疗,治疗3个月;选择52例健康体检者为对照组,两组治疗前后均进行24h动态血压监测并记录两组血脂各项指标的变化。结果治疗前,观察组患者血压及血脂各项指标均高于对照组;治疗后,观察组患者总胆固醇无改变(P>0.05),高密度脂蛋白升高,甘油三酯、低密度脂蛋白及血压均下降(P<0.05)。结论 OSAHS患者采用NCPAP可改善其高脂血症并降低血压。
Objective To investigate the influence of nasal continual positive airway pressure （ NCPAP） on blood pressure and lipid of patients with obstructive sleep apnea hypopnea syndrome （ OSAHS） . Methods 52 pa-tients with OSAHS were selected as the observation group, given NCPAP treatment for three months, and 52 cases without OSAHS were selected as the control group. They were all given 24 hour dynamic blood pressure monitoring and the changes of blood lipid were recorded in the two groups. Results Before the treatment, the blood pressure and indexes of lipid were higher in the observation group than in the control group （P〈0. 05）. After the treatment, TC showed no change in the observation group （P〉0. 05）, but HDL increased and TG, LDL and BP decreased in the observation group （P〈0. 05）. Conclusion NCPAP can improve hyperlipoidemia and decline blood pressure in the treatment of patients with OSAHS.
出处
《临床肺科杂志》
2014年第7期1258-1260,共3页
Journal of Clinical Pulmonary Medicine
关键词
阻塞性睡眠呼吸暂停综合症
持续无创正压通气
血脂
血压
obstructive sleep apnea hypopnea syndrome
nasal continual positive airway pressure
bloodlipid
blood pressure
