摘要
目的：探讨甘肃省藏族和汉族妇女绝经前和绝经后骨强度变化。方法采用GE EXPRESSⅡ超声骨密度测量仪对109例年龄40～52岁绝经前和100例年龄53～60岁绝经后藏族妇女与55例年龄40～52岁绝经前和72例年龄53～60岁绝经后汉族妇女进行骨强度对比分析。测量右脚跟骨的骨强度、骨质情况，通过计算T值和Z值，评估藏族和汉族妇女绝经前和绝经后骨强度变化和骨折风险。结果1．藏族和汉族妇女绝经前骨强度指数明显均高于绝经后藏族和汉族妇女；藏族妇女和汉族妇女两者之间对比无差别（t＝7.408，P＝0.000；t＝4.903，P＝0.000）。2．藏族和汉族妇女绝经后骨质少孔和骨质疏松检出率明显高于绝经前藏族和汉族妇女；藏族和汉族妇女两者之间对比无差别（χ2＝7.928，P＝0.000；χ2＝7.723，P＝0.021）。结论1．绝经后藏族和汉族妇女骨质流失较严重，应及时补充雌激素和钙剂，预防骨质疏松的发生。2．由于少数民族与汉族长期居住在一起，生活和饮食习惯逐渐相近及地理环境相同，使得绝经前和绝经后藏族妇女与绝经前和绝经后汉族妇女骨强度变化、骨质少孔及骨质疏松检出率无明显差别。
Objective To investigate the bone strength change between Tibetan and Han women in premenopausal and postmenopausal period in Gansu province.Methods A total of 209 Tibetan women, including 109 premenopausal women （40-52y） and 100 postmenopausal women （53-60y）, and 127 Han women, including 55 premenopausal women （40-52y） and 72 postmenopausal women （53-60y）, were selected.The bone mineral density （BMD） and bone condition of the right calcaneus were detected using GE EXPRESS II ultrasonic bone mineral density detector.The T value and Z value were calculated in order to evaluate the fracture risk and to monitor the bone strength change during premenopausal and postmenopausal period in Tibetan and Han women.Results The bone strength index in Tibetan and Han premenopausal women was significantly higher than that in Tibetan and Han postmenopausal women （t=7.408, P=0.000; t=4.903, P=0.000）.The positive rate of less bone holes and osteoporosis in Tibetan and Han postmenopausal women was higher than that in Tibetan and Han premenopausal women （χ2 =7.928, P=0.000; χ2 =7.723, P =0.021）, while no significant difference between Tibetan and Han women was observed. Conclusion The bone loss in Tibetan and Han postmenopausal women is serious .Since the Tibetan and Han people have lived together for a long time and share the same diet habit and geographic environment , no obvious difference of bone strength index , positive rate of less bone holes , and osteoporosis exists between Tibetan and Han women during the premenopausal and postmenopausal＆amp;nbsp;period.
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2014年第5期521-523,534,共4页
Chinese Journal of Osteoporosis
基金
科技部基础专项(2012FY110900)
甘肃省自然基金(1308RJZA170)
甘肃省自然基金(1308RJZA182)
西北民族大学科研创新团队(xbmucxtd-2011-1)
关键词
骨强度
绝经前
绝经后
藏族
汉族
Bone strength
Premenopausal
Postmenopausal
Tibetan women
Han women
