摘要
目的探讨左心房容积指数(LAVI)在评价充血性心力衰竭患者左心室舒张功能中的作用。方法入选慢性收缩性心功能不全(LVEF<50%)合并三尖瓣反流的患者共188例。按照心功能分级分析其临床资料:包括年龄、性别、伴随疾病(高血压、糖尿病、高脂血症、冠心病、心肌病)、服药史;超声心动图资料:各腔室大小、室壁厚度、LVEF、E峰、A峰、EDT、Em、E/A、E/Em、PAPS、TR程度、MR程度;生化指标:N末端B型利钠肽原(NT-ProBNP)血浆水平及之间的相关性。结果 (1)E/Em随着心功能的恶化而增加,且具有统计学意义(P<0.001)。但在NYHA2、3、4级分组之间,E/Em在组间的差异无显著性(P=0.381);而LAVI亦随着NYHA分级的增加而增加(P<0.001),在NYHA2、3、4级分组之间差异亦具有统计学意义(P<0.001)。(2)LAVI、E/Em与NT-proBNP、肺动脉收缩压(PASP)的有相关性(r:0.468,0.405,0.594,0.303,P<0.001)。结论 LAVI是评价慢性收缩性心力衰竭患者左心室舒张功能较理想的指标。
Objective To explore the value of left atrial volume index（LAVI） in evaluating left ventricular diastolic function of congestive heart failure patients. Methods The study group included 188 patients of congestive heart failure （ LVEF 〈 50% ） with tricuspid regurgitation. The basic information including age, sex, accompany disease, medication history ; eehoeardiographic diagnosis reports contaning the chamber size, wall thickness, LVEF, Epeek, Apeek, EDT, Era, E/A, E/Era, PAPS, degree of mitral regurgitation and tricuspid regurgitation ; NT-ProBNP plasma levels of patients were analyzed according to NYHA Grades. Results （ 1 ） There was statistical diffarenees in E/Era and LAVI among four groups of different NYHA Grades. However, among NYHA Grades 2,3,4, LAVI was superior to E./Em in assessing left ventricular diastolic function of severe congestive heart failure patients（P 〈 0. 001 vs. P = O. 381 ）. （2） Both of LAVI and E/Era were correlated statistically with NT-proBNP and pulmonary artery systolic pressure（PASP） （ r ：0. 468,0. 405,0. 594,0. 303, P 〈 0. 001 ）. Conclusions LAVI is an ideal marker of left ventricular diastolic function evaluation in severe congestive heart failure patients.
出处
《中华临床医师杂志（电子版）》
CAS
2013年第2期44-47,共4页
Chinese Journal of Clinicians(Electronic Edition)
关键词
心力衰竭
收缩性
心室功能
左
利钠肽
脑
左心房容积指数
肺动脉收缩压
Heart failure, systolic
Ventricular function, left
Natriuretic peptide, brain
Left atrial volume index
Pulmonary artery systolic pressure
