摘要
目的:优选腰痛颗粒剂中生物碱的最佳提取工艺。方法:采用正交试验法,以干浸膏得率、防己总碱和粉防己碱提取率为考察指标,优选总生物碱的渗漉工艺。结果:确定了最佳工艺条件为粉碎度为粗粉、乙醇浓度为60%、浸泡时间为48h,渗漉速度为2 ml·min-1·kg-1。结论:该工艺简便、快捷、稳定,可为生产提供理论依据。
To study the optimum extraction conditions for Yaotong granules. Methods： An orthogonal test was adopted to optimize the percolation extraction process of total alkaloids by orthogonal experiment with the yield of dry extract and total extraction rate of tetrandrine and fangchinoline as the indices. Results： The optimal extraction conditions were as follows ： the medicinal materials were soaked with crude powder in 60% ethanol for 48h,then percolated at the rate of 2 ml·min^-1·kg^-1. Conclusion： The extraction technology for Yaotong granules is simple and rapid with stable results, which can provide theoretical basis for the production of Yaotong granules.
出处
《中国药师》
CAS
2014年第5期757-760,共4页
China Pharmacist
基金
武汉市科技攻关计划项目(编号:武科计[2010]43号
201060938365-03)
关键词
腰痛颗粒剂
总生物碱
提取工艺
正交试验
Yaotong granules
Total alkaloids
Extraction technology
Orthogonal test
