摘要
建立高效液相色谱法测定蓝芩口服液中的栀子苷含量的方法.色谱柱:Kromasil C18柱;流动相:0.05mol·L-1磷酸氢二钠-甲醇(70:30);流速1.0ml·min-1;检测波长238nm.栀子苷在9.6～48.0μg·ml -1之间峰面积与浓度呈良好的线性关系,r =0.9999,平均回收率为98.5%(n =6),RSD为0.66% . 该方法可用于蓝芩口服液中栀子苷的质量控制.
A HPLC method for the determination of geniposide in Lanqin Oral Liquid was established. A Kromasil C18 column was used with 0.05mol · L^-1 Na2HPO4 and methanol （70 ： 30） as the mobile phase. The flow rate was 1.0ml · min^-1 , and the detecting wavelength was 238nm. There was a good linear relationship （r=0. 9999） when the concentration range of geniposide was 9.6-48.0μg · ml^-1. The average recovery was 98. 5% （n= 6）, RSD=0. 66%. The method could be used in quality control of geniposide in Lanqin Oral Liquid.
出处
《中国药事》
CAS
2005年第11期667-669,共3页
Chinese Pharmaceutical Affairs
