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体外受精和胚胎移植妊娠后发生肺结核11例临床分析 被引量:5

Clinical characteristics of pulmonary tuberculosis in pregnant women after in vitro fertilization-embryo transfer
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摘要 目的 分析体外受精和胚胎移植(IVF-ET)后妊娠发生急性血行播散性肺结核的临床特点.方法 回顾性分析2003年1月至2012年10月在杭州市红十字会医院治疗的IVF-ET后妊娠并发血行播散性肺结核的1 1例患者的临床资料.结果 IVF-ET后妊娠并发急性血行播散性肺结核患者的临床表现多不典型,均以发热为主要表现,可伴有头痛,呼吸道症状隐匿,胸部影像学表现以粟粒性结节改变为主.3例妊娠患者人工流产终止妊娠,其余8例均在发病后2~5周内发生自然流产.结论 IVF-ET后妊娠发生血行播散性肺结核的妊娠结局差,对抗炎治疗无效的IVF-ET发热患者应警惕结核病,尽早行结核病的相关检查. Objective To analyze the clinical characteristics of acute hematogenous pulmonary tuberculosis and tuberculous meningitis in pregnant women after in vitro fertilization and embryo transfer (IVF-ET).Methods Clinical data of 11 cases of hematogenous pulmonary tuberculosis and tuberculous meningitis in women after IVF-ET admitted in Hangzhou Red Cross Hospital from January 2003 to October 2012 were retrospectively analyzed.Results The clinical manifestations of acute hematogenous pulmonary tuberculosis and tuberculous meningitis were non-specific.All cases presented with fever,and some were accompanied by headache,but no typical respiratory manifestation was observed.Chest X-ray showed typical military lesions.Miscarriage occurred in 11 patients within 2 to 5 weeks after the onset of fever,including 3 received artificial abortion.Conclusions The outcome of hematogenous pulmonary tuberculosis in pregnant women after IVF-ET is less favorable.Physicians should be aware of tuberculosis in pregnant women after IVF-ET,especially for those with long-term fever and not responding to anti-inflammatory treatment.
出处 《中华临床感染病杂志》 CAS 2014年第2期137-139,共3页 Chinese Journal of Clinical Infectious Diseases
关键词 结核 结核 粟粒性 结核 脑膜 受精 体外 胚胎移植 Tuberculosis, pulmonary Tuberculosis, military Tuberculosis, meningeal Fertilization in Vitro Embryo transfer
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