摘要
目的采用超声评价妊娠期糖尿病孕妇胎儿的心脏结构及功能的改变情况。方法选择2012年1～12月于本院分娩的60例确诊为妊娠糖尿病的孕妇,同期孕周匹配的正常妊娠孕妇60例为对照组,两组均在妊娠末期行胎儿超声心动图检查,测定胎儿左/右心室收缩末期内径（LVDs、RVDs）、舒张末期内径（LVDd、RVDd）,左/右室壁厚度（IVWT、RVWT）,室间隔收缩、舒张末期厚度（IVSs、IVSd）;并计算左室射血分数（LVEF）,二尖瓣和三尖瓣E、A峰值流速比值（E/AMV、E/ATV）,以及心室Tei指数,并进行组间比较。结果两组胎儿LVDs、RVDs、LVDd、RVDd差异无统计学意义（P〉0.05）,糖尿病组胎儿LVWT、RVWT、IVSs、IVSd均明显高于对照组,组间差异有统计学意义（P〈0.05）。两组LVEF差异无统计学意义;糖尿病组左、右心输出量均明显高于对照组（P〈0.05）,E/ATV低于对照组（P〈0.05）;糖尿病组左、右心室Tei指数明显高于对照组（P〈0.05）。结论妊娠糖尿病孕妇胎儿在心脏结构和功能方面较正常胎儿有明显改变,超声心动图可有效监测胎儿心脏功能情况,为早期干预和妊娠处理提供依据。
Objective To evaluate cardiac structural and functional changes of fetuses whose mothers have gestationed diabetes. Methods 60 cases of pregnant women（diagnosed as gestational diabetes mellitus） delivered in our hospital from January to December 2012 were selected as the experimental group, and 60 cases of normal pregnant women with gestational age in the same period were selected as the control group. Patients in both of the two groups were given fetal echocardiography in late pregnancy to measure left/right ventricular systolic diameters（LVDs, RVDs）, left/right ventricular diastolic diameter（LVDd, RVDd）, left/ right ventricular wall thickness（IVWT, RVWT）, and inter-ventricular septum shrink/diastolic thickness（IVSs, IVSd）; meanwhile left ventricular ejection fraction（LVEF）, mitral and tricuspid E, A peak velocity ratio（E/ AMV, E/ATV）, and ventricular Tei indexes were calculated. And all measures were compared between the two groups. Results There were no signifi cant differences between the two groups on LVDs, RVDs, LVDd, RVDd（P0.05） while the values of LVWT, RVWT, IVSs, IVSd of the diabetes group were higher than those of the control group with signifi cant differences（P0.05）. There was no signifi cant difference between the two grou1ps on LVEF values while the left and right cardiac output values of the diabetes group were signifi cantly higher than those of the control group（P0.05）, E/ATV values of the diabetes group were lower than those of the control group（P0.05）; the left and right ventricular Tei index values of the diabetes group were signifi cantly higher than those of the control group（P0.05）. Conclusion The cardiac structures and functions of fetus of pregnant women with gestational diabetes are significantly changed compared with normal fetuses. Echocardiography can effectively monitor the fetal cardiac functions, and provide the basis for early intervention and treatment of pregnancy.
出处
《中国医疗设备》
2014年第5期161-163,共3页
China Medical Devices
