摘要
目的:优选三黄膏巴布剂的最佳基质配比,为其成型工艺研究提供依据。方法:分别以涂展性、均匀性、剥离性、皮肤追随性及外观为指标,采用L9(34)正交实验表对三黄膏巴布剂的基质配方进行优选研究,以确定其最佳配比组合。结果:三黄膏巴布剂最佳基质配比为甘油1.2 mL,聚丙烯酸钠0.5 g,羧甲基纤维素钠0.2 g,明胶0.2 g。结论:按照优选基质配方制成的三黄膏巴布剂膏体柔软,粘性适度,皮肤追随性好,剥离不残留,保湿性、涂展性良好,此基质配方可使用于三黄膏巴布剂的制剂生产。
Objective： To provide evidence for the formation technology ofSanHuangcataplasm by optimizing the best matrix ratio of the cataplasm. Methods： Matrix formula ofSanHuangcataplasm was studied with L9（34） or-thogonal design by taking spread, the distribution, detachment, skin tracing ability and the appearance as the indexes, to ensure the best ratio of the cataplasm. Results： The optimal matrix formula ofSanHuangcataplasm contained： glycerol, 1.2mL, sodium polyacrylate, 0.5 g, sodium carboxymethylcellulose, 0.2 g and gelatin, 0.2 g. Conclusion： The matrix formula could be used to the product ofSanHuangcataplasm.
出处
《西部中医药》
2014年第5期22-24,共3页
Western Journal of Traditional Chinese Medicine
基金
兰州市科学技术项目(编号2011-2-32)
关键词
三黄膏巴布剂
正交设计
基质配方
成型工艺
SanHuang cataplasm
orthogonal design
matrix formula
formation technology
