摘要
目的了解医院抗菌药物使用情况,为临床合理用药提供参考。方法调查2011年和2012年所有出院患者的临床资料,分析总体抗菌药物使用情况。结果 2011年和2012年的患者分别为41 691例和43 872例,与2011年相比,2012年医院患者在抗菌药物使用强度及抗菌药物使用率等指标上均有所下降,抗菌药物治疗的患者微生物检验样本送检率有所上升;两年抗菌药物临床使用均以氟喹诺酮类和青霉素类+酶抑制剂类为主,氟喹诺酮类的使用强度分别为10.88和11.29,青霉素类+酶抑制剂类的使用强度分别为9.22和8.13;左氧氟沙星、莫西沙星和头孢米诺的使用强度均排在前3位,2011年使用强度分别为5.29、4.56、4.74,2012年使用强度分别为5.66、5.10、3.85。结论医院抗菌药物管理在总体上已经取得一定效果,但在抗菌药物的使用上还需要出台具体措施,加强管理控制。
OBJECTIVE To understand the use of antibiotics so as to provide guidance for reasonable clinical use of antibiotics. METHODS The clinical data of all the patients who were discharged in 2011 and 2012 were investiga- ted, and the overall use of antibiotics was analyzed. RESULTS Totally 41 691 patients in 2011 and 43 872 patients in 2012 have been investigated. As compared with 2011, the intensity of use of antibiotics and the utilization rate were decreased in 2012, while the submission rate of the microbiological examination samples was increased. The fluoroquinolones and penicillin plus enzyme inhibitors were the most frequently antibiotics in the two years; the in- tensity of use of fluoroquinolones was 10.88 in 2011, 11.29 in 2012; the intensity of use of penicillin plus enzyme inhibitors was 9.22 in 2011, 8.13 in 2012. The intensity of use of levofloxacin was 5.29 in 2011, 5.66 in 2012; the intensity of use of moxifloxacin was 4.56 in 2011, 5.10 in 2012; the intensity of use of cefminox was 4.74 in 2011, 3.85 in 2012. CONCLUSION The management of use of antibiotics has achieved certain effect and still need to introduce specific measures for use of antibiotics and strengthen the management and control.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第10期2422-2424,共3页
Chinese Journal of Nosocomiology
基金
温州市科技局基金资助项目(Y20090383)
