摘要
采用一步法,以聚多巴胺(PDA)为还原剂和保护剂,制备PDA功能化的纳米银粒子(PDA-nanoAg)。提出PDA-nanoAg合成机理,并考察其在水相中的分散稳定性。通过紫外-可见吸收分光光度计(UV-Vis)、透射电子显微镜(TEM)、傅里叶变换红外光谱仪(FTIR)对产物形貌和结构进行表征。采用肉汤稀释法测试PDAnanoAg的抗菌性能。结果表明,所制备的PDA-nanoAg平均粒径为50 nm,具有良好的稳定分散性;对埃希氏大肠杆菌(E.coli)、金黄色葡萄球菌(S.aureus)的最小抑菌浓度(MIC)为7.56 mg/L,最小杀菌浓度(MBC)为30.24mg/L。
Polydopamine （PDA） functionalized silver nanoparticles （PDA-nanoAg） were synthesized by one-step method with PDA as the reductant and protectant. The mechanism for the preparation of PDA- nanoAg was proposed. The stable dispersion duration of the as-synthesized Ag nanoparticles in water was also observed. The structure and morphology of PDA-nanoAg particles were investigated by ultraviolet-visible （ UV-Vis ） absorption spectroscopy, transmission electron microscopy （ TEM ）, and Fourier-transform infrared （FTIR） spectrometry. The antibacterial activity of PDA-nanoAg nanoparticles against Escherichia coli （ E. coli ） and Staphylococcus aureus （ S. aureus ） were investigated by broth dilution. The results indicate that the average diameter of the Ag nanoparticles was 50 nm, and PDA- nanoAg particles exhibited good stability in water over a long period of time. The minimal inhibitory concentration（ MIC ） and the minimal bactericidal concentration （MBC） of the as-synthesized Ag nanoparticles against E. coli and S. aureus were 7.56 ma/L and 30. 24 ma/L. resnectivelv.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2014年第5期545-550,共6页
Fine Chemicals
基金
国家自然科学基金资助项目(50903011
51273220)
西南民族大学研究生创新型科研项目(CX2013SZ33)~~
关键词
纳米银
聚多巴胺
机理
抗菌性
功能材料
Ag nanoparticles
polydopamine
mechanism
antibacterial property
functional materials
