摘要
目的探讨踝臂指数(ABI)和同型半胱氨酸(Hcy)对2型糖尿病合并急性心肌梗死的预测价值。方法选择2型糖尿病合并急性心肌梗死患者30例作为观察组,同期选择单纯2型糖尿病患者,未发生心脑血管事件者30例作为对照组,分别测定两组患者的ABI及血清Hcy。结果两组患者血压(BP)、空腹血糖(FPG)、餐后2小时血糖(2hPG)、胆固醇(CHO)、甘油三酯(TG)、低密度脂蛋白(LDL-C)等比较差异无统计学意义(P>0.05)。观察组ABI值平均为(1.03±0.10),对照组为(1.10±0.06),两组比较差异有显著统计学意义(P<0.01);观察组Hcy水平为(12.59±4.26)umol/L,高于对照组(9.65±2.42)umol/L,两组比较差异有显著统计学意义(P<0.01);ABI与Hcy呈负相关(r=-0.292,P<0.05)。结论对Hcy与ABI进行测定,可对2型糖尿病患者未来发生心肌梗死的风险作出预测,减少急性心肌梗死的发生。
Objective To study the predictive value of Ankle brachial index （ABI）and homocysteine （Hcy）in type 2 diabetes with acute myocardial infarction .Methods 30 cases of observation group were type 2 diabetes with acute myocardial infarction , and 30 cases of control group were not with cardiovascular and cerebrovascular events .ABI and Hcy were observed .Results There were no statistical differences in the average blood pressure （BP） ,fasting plasma glucose （FPG） ,2-hour postprandial blood glucose （2 hPG） ,cholesterol （CHO） ,triglycerides （TG） ,low density lipoprotein cholesterol （LDL-C） between two groups（P〉0.05） .The average ABI of observation group was 1.03 ± 0.10 ,and which of control group was 1.10 ± 0.06 ,there was statistically significant differences between two groups （P〈0.01） .The average Hcy of observation group was 12.59 ± 4.26 umol/L ,and which of control group was 9.65 ± 2.42 umol/L ,there was statistically significant differences between two groups（P〈0.01） .There was negative correlation between ABI and Hcy （r= -0.292 ,P〈0.05） .Conclusion Determination of patients ,Hcy and ABI ,can effectively predict myocardial infarction in patients with type 2 diabetes in the future ,reduce the incidence of acute myocardial infarction .
出处
《滨州医学院学报》
2014年第2期110-113,共4页
Journal of Binzhou Medical University
关键词
踝臂指数
同型半胱氨酸
2型糖尿病
急性心肌梗死
Ankle brachial index
Homocysteine
Type 2 diabetes
Acute myocardial infarction
