摘要
海绵由于其独特的生理结构、进食方式使其体内部聚集了大量的微生物,这些微生物产生了多种结构新颖的生物活性物质,因此海绵及其共附生微生物的研究成为了海洋药物研发的热点。就海绵中共附生真菌的分布情况,新技术的应用及其生物次级代谢产物的生物活性展开综述。
Because of the unique physiological structure and digest system, marine sponges enrich large numbers of microorganisms. Lots of novel bioactive compounds were isolated and identified from sponges-associated fungi, which is highlight in marine drug discovery. The development on the distribution of fungi, the application of new technique, novel bioactive secondary metabolites and biological activities were reviewed.
出处
《生物技术通报》
CAS
CSCD
北大核心
2014年第4期36-42,共7页
Biotechnology Bulletin
基金
国家"863"计划项目(2011AA090701)
