摘要
目的探讨增强型体外反搏(Enhanced External Counter Pulsation,EECP)在老年冠心病患者康复治疗中的应用。方法 48例老年冠心病患者平分为两组,对照组(n=24)常规给予双联抗血小板(阿司匹林和硫酸氯吡格雷)、β受体阻滞剂、ACEI、他汀类调脂药物、胸痛时给予硝酸盐制剂等;治疗组(n=24)在常规药物治疗基础上加用增强型体外反搏。观察两组患者心绞痛疗效、心肌梗死发生率、心血管病住院率、心功能分级变化、左室射血分数(LVEF)等指标及应用增强型体外反搏的安全性、耐受性。结果治疗组的心绞痛疗效明显高于对照组(P<0.05),治疗组的心肌梗死发生率和心血管病住院率与对照组相比无显著性(P>0.05);对照组心功能分级、LVEF值无明显变动,而治疗组有显著提高(P<0.05)。治疗组无发生严重不良反应,提示EECP耐受性良好。结论增强型体外反搏在老年冠心病患者的康复治疗中可以提高心绞痛的疗效,提高运动耐量,改善左室的收缩功能,且安全性、耐受性好,值得推广应用。
Objective To explore the application of enhanced external counterpulsation in rehabilitation therapy for gerontal patients with coronary heart disease. Methods 48 cases of gerontal patients with eoronary disease were divided into two groups averagely, and patients in the control group were routinely treated with antiplatelet agents (aspirin and clopidogrel sulfate), beta- blockers, ACEI, statins, nitrate drugs (when suffering ehest pain). The patients in treatment group were extra treated with EECP based on routine treatment. We observed and recorded the clinical effect of angina pectoris, incidence of myocardial infarction, admission rate of CV, change of cardiac functional grading, LVEF, security and tolerance of EECP. Results The clinical effeet of angina pectoris of the treatment group was better than that of the control group( P 〈 0.05 ). And the ineidence of myocardial infarction and admission rate of CV present no difference between the two groups ( P 〉 0. 05 ). The cardiac funetional grading and LVEF of the control group are invariant while those of the treatment improved obviously(P 〈 0. 05). There is no serious untoward effect happened in the treatment group, it means that the tolerance of EECP is fine. Conclusions EECP was safe and well in toleranee, it eould improve the clinical effect of angina peetoris in the rehabilitation therapy for gerontal patients with CHD, and increase the exercise tolerance, ameliorate systolic function of left ventricle.
出处
《齐齐哈尔医学院学报》
2014年第7期979-980,共2页
Journal of Qiqihar Medical University
关键词
增强型体外反搏
老年冠心病
康复治疗
Enhanced external counterpulsation
Gerontal coronary disease
Rehabilitation therapy