摘要
目的观察硫酸氯吡格雷(波立维)联合阿司匹林肠溶片治疗非ST段抬高型心肌梗死(NSTEMI)的临床疗效。方法 NSTEMI患者180例随机分为观察组和对照组各90例。对照组在常规治疗基础上给予波立维治疗;观察组在对照组治疗基础上加服阿司匹林肠溶片。2组疗程均为8周。观察比较2组的临床疗效和心脏不良事件。结果观察组总有效率为94.4%高于对照组的81.1%,心脏不良事件发生率为0低于对照组的7.8%,差异均有统计学意义(P<0.05)。结论波立维联合阿死匹林肠溶片治疗NSTEMI,临床效果显著,不良反应小,安全可靠。
Objective To observe clopidogrel and aspirin enteric-coated tablets in the treatment of non-ST-segment elevation myocardial infarction.Methods 180 cases of NSTEMI patients were randomly divided into control group and observation group with90 patients in each.The control group was given clopidogrel based on conventional treatment,while the observation group was treated with enteric-coated aspirin tablets based on the control group.Both groups were treated for 8 weeks.The clinical efficacy and adverse cardiac events were observed and compared.Results The total effect rate in observation group was 94.4%,with no progress to acute myocardial infarction and no death;but in control group,the total effect rate was 81.1%,and 4 patients（7.8%）progressed to acute myocardial infarction,and the difference was statistically significant（P0.05）.Conclusion Clopidogrel and aspirin enteric-coated tablets in the treatment of non-ST-segment elevation myocardial infarction is effect,safe and reliable.
出处
《临床合理用药杂志》
2012年第2期4-5,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
波立维
阿司匹林肠溶片
非ST段抬高型心肌梗死
疗效
Clopidogrel
Enteric-coated aspirin tablets
Non-ST-segment elevation myocardial infarction（NSTEMI）
Effect
