摘要
目的了解我国自然人群中新型ＤＮＡ病毒－输血传播病毒（ＴＴＶ）的感染情况。方法采用套式聚合酶链反应法 （ｎＰＣＲ）检测云南某自然村的 １７９位村民血清及粪便 ＴＴＶ ＤＮＡ，并对检测结果及调查情况作统计学分析。结果自然人 群中 ＴＴＶ感染率约 １０．６％，感染者血清 ＡＬＴ正常，不同性别、年龄及民族的 ＴＴＶ ＤＮＡ阳性率无统计学差异；部分血清 ＴＴＶ ＤＮＡ阳性者粪便中可检测到 ＴＴＶ ＤＮＡ。结论我国自然人群中存在 ＴＴＶ无症状感染者，粪－口传播可能是 ＴＴＶ 感染的传播途径之一。
Objective To investigate the transmission of a novel DNA virus, transfusion-transmitted virus (TTV) among the residents in a natural village of Yunnan Province. Methods The serum and feces collected from 179 residents in the natural village were examined by nest polymerase chain reaction for detecting TTV, and statistical analyses of the results were performed. Results A total of 19 (10.6%) out of the 179 residents were found positive for TTV DNA in the serum, and TTV DNA was detected in 6 out of tile 114 examined fecal samples. Six residents were TTV-positive in both the serum and feces. Signifi- cant difference in TTV positivity of the subjects categorized by different genders, ages and nationalities was not obsrved (P>0.05). Conclusion Asymptomatic infection of TTV is present in the natural population in China, and fecal-oral route might be another propergation mode of TTV.
出处
《第一军医大学学报》
CSCD
北大核心
2001年第3期199-201,共3页
Journal of First Military Medical University
基金
军队医学卫生科研基金九五重点资助项目!(98Z073)
