摘要
用ABC法对猴、猫前庭神经核簇(VN)内谷氨酸和胆碱乙酰化酶免疫反应阳性(Cluir和ChATir)神经元胞体的形态和分布作了观察和比较。发现两种细胞构筑的差异与所在部位的神经联系及功能相关。前庭神经上核(SVN)中央部、前庭神经外侧核(LVN)腹侧部、前庭神经内侧核(MVN)头侧半及y群的Gluir神经元是前庭眼肌反射的第一中继站。LVN的大型Gluir神经元以及前庭神经下核(IVN)尾侧半和MVN内数最占绝对优势的Gluir神经元构成前庭脊髓束的起始核。MVN、IVN尾侧半与SVN周围部的ChATir神经元参与VN的中枢协调机制,并可能作为内源性胆碱能神经元影响VN神经元的紧张性活动。
The distributions of Glu-and ChAT-immunoreactive neurons were investigated in the vestibular nuclei of the squirrel monkey and cat using purified antisera to Glu and ChAT respectively and avidin-biotin peroxidase complex.The question of whether Glu and ChAT immunocytoarchitetconic areal differences in VN could be correlated with differences in connections was discussed.Prevalent Gluir neurons in central SVN, ventral LVN, rostral MVN and group y suggested their serving as relays in the basic arcs of vestibular-ocular reflexes. Abundent Gluir giant neurons in LVN and Gluir neurons in MVN and caudal IVN absolutely prevailed over ChATir neurons in number reminded us of their effects over the motor neurons of spinal cord through vestibulospinal tract. While, the ChATir neurons in MVN, caudal IVN and peripheral SVN might play a role in central vestibular integrative mechanisms and act as intrinsic cholinergic neurons.
出处
《贵阳医学院学报》
CAS
1991年第2期152-157,共6页
Journal of Guiyang Medical College
关键词
前庭神经核
谷氨酸
胆碱乙酰化酶
vestibular nuclei
glutamate
choline acetyltransferase
immunohistochemistry
squirrel monkey
cat
