摘要
目的 :探讨先天性心脏病 (先心病 )对患儿脑干发育的影响。方法 :探讨先心病患儿听性脑干反应(ABR) ,并以正常儿为对照组。结果 :年龄 <12月 ,青紫型先心病 (CCHD)患儿Ⅰ波潜伏期 (LP)正常 ,Ⅰ～Ⅴ波峰间潜伏期 (IPL)较正常儿显著延长 ,非青紫型先心病 (NCCHD)患儿Ⅰ波LP、Ⅰ～Ⅴ波IPL均显著延长 ;4～ 6岁者NCCHD和CCHD无反复缺氧发作者LP和Ⅰ～Ⅴ波IPL与正常儿无差异 ,CCHD反复缺氧发作者Ⅰ～Ⅴ波IPL较正常儿显著延长 ,异常率 2 3%。结论 :先心病不延迟婴儿期脑干发育 ,缺氧发作可损害脑干功能 。
Objective:To evaluate the influence of congenital heart disease (CHD) on the development of brainstem in children.Method:The auditory brainstem response(ABR) was studied and compared with normal control.Results:In the study group aged under 12 months,latent period(LP) of wave I in cyanotic congenital heart disease(CCHD) was normal,and interpeak latency(IPL) from waves I to V was prolonged,while they were all prolonged in non-cyanotic congenital heart disease(NCCHD).In the group aged 4 to 6 years,LP of wave I and IPL of waves Ⅰ～Ⅴ in NCCHD patients and CCHD patients without repeated hypoxia were normal while IPL of waves Ⅰ～Ⅴ in CCHD patients with repeated hypoxia was evidently prolonged.The abnormality rate was 2.3%.Conclusion:CHD do not delay the development of brainstem,but ischemia attacks may harm brainstem function,so early intervention is needed for ischemia attack patients.
关键词
儿童
诱发电位
先天性心脏病
听性脑干反应
Heart affects,congenital
Child
Evoked potentials,auditory,brain stem
