摘要
目的探讨多重耐药鲍曼不动杆菌(MDR-Ab)耐药株产生的危险因素及预防措施。方法将重症医学科实验室培养确诊MDR-Ab感染的肺炎病例31例作为病例组,以单纯随机抽样方式挑选同时期重症医学科非MDR-Ab院内感染病例31例作为对照组。结果两组患者在年龄、性别、基础疾病和在使用碳青霉烯类及β-内酰胺酶抑制剂抗生素方面无统计学差异(P>0.05)。两组患者在住院时间、机械通气时间、三代头孢使用量等有统计学差异(P<0.05)。结论长时间住院、长时间接受机械通气是鲍曼不动杆菌医院感染肺炎的危险因素,大量三代头孢的过度使用,进一步诱导了MDR-Ab的产生。
Objective To discuss the risk factors for the development of multidrug-resistant acinetobacter baumanni and preventive measures.Methods 31 patients with multidrug-resistant Acinetobacter baumannii and 31 patients with non— multidrug-resistant acinetobacter baumanni were analyzed.Results There was no significantly difference of age,gender,basic disease,the use of carbapenems and beta-lactam antibiotics between the two groups.There were statistic significant in length of hospital stay,use of mechanical ventilation,and the use of third generation cephalosporin.Conclusions The risk factors of HAP caused by A.baumanni includes long stay in hospital,mechanical ventilation for a long time and the overuse of third generation cephalosporin further induce the appearance of MDR-A.baumanni.
出处
《西部医学》
2014年第4期428-429,434,共3页
Medical Journal of West China
基金
国家自然科学基金(81071587)
关键词
多重耐药鲍曼不动杆菌
医院感染
三代头孢
Acinetobacter baumannii
Hospital Infection
Third generation cephalosporin
