摘要
目的 探讨医院获得性急性肾损伤（Hospital-Acquired acute kidney injure,HA-AKI）的致病因素、高危因素及治疗方法,以改善HA-AKI患者预后.方法 回顾性分析200例（老年组120例,非老年组80例）HA-AKI患者的临床资料,对比分析两组患者的病因、高危因素、治疗方法及预后.结果 两组HA-AKI致病因素明显不同,且存在多种危险因素,老年组以未及时控制的原发病或慢性肾脏病基础急性加重（32％）、药物损伤（30％）、低血容量（25％）为主.非老年组以手术损伤（29、4％）、其他（29％）为主.非老年组肾损伤程度显著低于老年组（P＜0.05）;非老年组合并原发慢性病的百分率低于非老年组（P＜0.05）;老年组存在多器官功能障碍综合征（MODS）者显著高于非老年组（P＜0.05）;老年组需要肾脏替代治疗组显著高于非老年组（P＜0.05）;非老年组的预后显著好于老年组（P＜0.05）.结论 临床上HA-AKI非常多见,且逐渐增多,早期诊断和干预HA-AKI,可明显改善患者的预后和生活质量.
Objectives Hospital-acquired acute kidney injury （at-Acquired acute kidney injure,HA -AKI） of pathogenic factors,risk factors and treatment.Methods In order to improving the prognosis of patients with HA-AKI.Method Retrospective analysis of 200 cases of （elderly group 120 cases,non elderly group 80 cases）the clinical data of the HA-AKI,Analysis of the cause of two groups of patients,risk factors,treatment and prognosis.Results Two groups of HA-AKI pathogenic factors are significantly different,And there are many risk factors,Elderly group failed to timely control of the primary disease or acute exacerbation of chronic kidney disease basis（32%）Drug damage（30%） Low blood volume（25%）,The elderly group to surgical injury（29.4%）,The other is given priority to（29%）,The renal damage of degree in non elderly group is significantly lower than elderly group（P 〈 0.05）,Non elderly group merged primary chronic disease percentage is lower than the non elderly group （P 〈 0.05）,Elderly group has multiple organ dysfunctionelderly group（P 〈 0.05）,Elderly group require renal replacement therapy group wa syndrome （MODS） were significantly higher than that of non elderly group higher than that of non significantly higher than that of non elderly group（P 〈 0.05）.Non elderly group was significantly better prognosis in the elderly group（P 〈 0.05）.Conclusions HA-AKI clinically is very see,and increase gradually,HA-AKI,early diagnosis and intervention can obviously improve the prognosis of patients and quality of life,Elderly group require in renal replacement therapy group was significantly.
出处
《国际泌尿系统杂志》
2014年第2期186-189,共4页
International Journal of Urology and Nephrology
关键词
肾疾病
急性病
Kidney Diseases
Acute Disease
