摘要
目的 探讨丙泊酚对无痛人工流产妇女麻醉苏醒后情绪的影响。 方法 将初次行无痛人工流产的未婚妇女120例采用随机数字表法随机分为2组，每组60例，分别采用丙泊酚（P组）和依托咪酯（E组）麻醉，两组均复合舒芬太尼。采用正性负性情绪量表（the positive and negative affect scale， PANAS）分别在术前和术后对人工流产妇女进行情绪评定。PANAS共20个形容词，其中描述正性情绪和负性情绪的各10项，每项有5个答案：几乎没有、比较少、中等程度、比较多和极其多，分别计1、2、3、4、5分。 记录两组术后恶心呕吐、头晕、腹痛及梦幻的发生情况。 结果 两组的一般资料、意识消失时间、麻醉苏醒时间、手术时间、术前血压、心率、术前正性情绪、负性情绪比较差异无统计学意义。麻醉后P组与E组比较，血压［（74±12） mmHg vs （79±13） mmHg（1 mm Hg=0.133 kPa）］和心率［（69±16） 次/min vs （74±17） 次/min］均降低（P〈0.05）。与术前比较： 术后P组负性情绪评分［（31±7） 分 vs （24±9） 分］和E组负性情绪评分［（30±8） 分 vs （25±7） 分］均降低（P〈0.05），P组正性情绪评分［（25±7） 分vs （34±8） 分］增高（P〈0.05），E组正性情绪评分差异无统计学意义（P〉0.05）。术后头晕、恶心、腹痛的发生率两组比较差异无统计学意义；P组梦幻发生率（36.7%）高于E组（13.3%）。麻醉满意度两组均达到100%。 结论 丙泊酚使得人工流产妇女术后更易表现出积极、热情等正性情绪，这种情绪变化与其起效快、苏醒快以及头晕、恶心发生率低无关。
Objective To investigate the effect of propofol on postoperative mood for women with artificial abortion. Methods One hundred and twenty cases of unmarried women scheduled for artificial abortion were randomly divided into two groups： propofol（group P） or etomidate （group E） in combination with sufentanil. The mood of women was evaluated preoperatively and postoperatively by the positive and negative affect scale（PANAS）. PANAS is composed of 20 adjectives, describing 10 of positive emotions and negative emotions, each of which has five answers, counted 1, 2, 3, 4, 5, respectively. Adverse reactions such as dreams, dizziness, abdominal pain and vomiting were recorded postoperatively. Results There were no significant differences in loss of consciousness time, awakening time, blood pressure, heart rate, the score of positive emotions, and the score of negative emotions between two groups preoperatively. After anesthesia, blood pressure and heart rate were lower in the group P than the group E[（74±12） mmHg vs（79±13） mmHg（1 mmHg=0.133 kPa）, （69±16） bpm vs （74±17） bpm, P〈0.05]. Lower negative emotions scores postoperatively was found compared to that preoperatively in the group P and group E[（24±9） vs （31±7）,（25±7） vs （30±8）, P〈0.05]respevtively. The score of positive emotions postoperatively was increased in the group P compared to that preoperatively[（25±7） vs（34±8）, P〈0.05], but no changes in the group E. No significance differences in the incidence of postoperative dizziness, nausea and abdominal pain was found between two groups. The incidence of dreams was 36.7% in the group P, and 13.3% in the group E. Conclusions Women anesthetized with propofol for artificial abortion were more likely to induce positive emotions postoperatively. The change of the mood is independent of its quick action of propofol and low incidence of dizziness and nausea.
出处
《国际麻醉学与复苏杂志》
CAS
2014年第4期320-323,共4页
International Journal of Anesthesiology and Resuscitation
关键词
丙泊酚
人工流产术
情绪
Propofol
Artificial abortion
Mood
