摘要
丙泊酚广泛用于麻醉诱导、维持和用于ICU镇静。除临床用药外，静脉注射丙泊酚可使人产生欣快感、愉悦、性幻想和去抑制。临床资料和动物实验研究发现丙泊酚存在滥用和依赖。现就丙泊酚滥用的一些临床报道和造成依赖的可能机制作一综述。．
Propofol is a relatively new intravenous short-acting anaesthetic widely used for induction and maintenance of anaesthesia. Propofol is also used to provide sedation in ICU. Besides medical use, propofol infusion not only causes euphoria and delight, but also induces sexual hallucinations and disinhibition. Clinical and animal data have indicated the potential for abuse and dependence of propofol. This review summarizes the clinical abuses of propofol and describes the potential mechanisms of propofol dependence.
出处
《国际麻醉学与复苏杂志》
CAS
2009年第1期56-58,69,共4页
International Journal of Anesthesiology and Resuscitation
基金
国家自然科学基金资助（30672031）
关键词
滥用
依赖性
丙泊酚
Propofol
Dependence
Abuse
