摘要
目的探讨大肠腺瘤性息肉内镜治疗后复发的相关因素,从而筛查出易复发的高危人群,为腺瘤性息肉患者的随访提供依据。方法回顾性分析2000年1月至2013年3月行大肠腺瘤性息肉切除患者在随访期间的复发情况。行单因素χ2检验及多因素Logistic回归分析进行统计推断,分析各种危险因素与腺瘤性息肉复发的相关性。结果随访期间共249例患者复发腺瘤,复发比例为26.83%。单因素分析显示,腺瘤复发与年龄,腺瘤数目、直径、部位、类型,瘤变程度,基底部及治疗方式有关,而与性别无明显相关性。多因素Logistic回归分析显示,年龄,腺瘤数目、直径、类型,瘤变程度,基底部是腺瘤复发的独立危险因素,而腺瘤部位及治疗方式并非独立危险因素。结论符合年龄>60岁、个数≥3个、直径>10 mm、绒毛状结构、高级别上皮内瘤变、无蒂等特点的患者属于高危人群,符合的因素越多,腺瘤复发率可能越高,需要密切随访。
Objective To investigate the correlative factors for the recurrence of adenomatous polyps after endoscopic treatment so as to screen out high risk people and to provide information for proper surveillance. Methods The data of the adenoma recurrence among patients undergone endoscopic polypectomy from January 2000 to March 2013 were retrospectively reviewed. Univariatex2 test and multivariate logistic regression analysis were performed to analyze the association between risk factors and adenoma recurrence. Results A total of 249 cases （26.83%） developed new adenomas during the follow-up. Univariate analysis indicated that adenoma recurrence was associated with age, number of ad- enomas, adenoma diameter, location, pathological type, grade of dysplasia, basilar part and treatment method, but not with gender. Logistic regression analysis revealed that age, number of adenomas, adenoma diameter, pathological type, grade of dysplasia, and basilar part were independent risk factors of adenoma recurrence whereas adenoma location and treatment method were not. Conclusion Patients aged 60 years, with adenoma number ≥3, diameter 〉 10 mm, villous, high grade of dysplasia and sessile adenoma, have high risk of adenoma recurrence. Adenomas tend to recur in patients with more risk factors; therefore, intensive surveillance is recommended.
出处
《山东大学学报（医学版）》
CAS
北大核心
2014年第3期92-95,100,共5页
Journal of Shandong University:Health Sciences
关键词
腺瘤性息肉
复发因素
高危人群
随访
Adenomatous polyp
Recurrence factor
High-risk group
Surveillance
