摘要
目的:分析某医院药品不良反应(ADR)发生的情况及给患者带来的危害,分析其发生的原因并探讨相应的防治措施。方法:收集我院ADR报告223例,分别从患者年龄、ADR表现、药品种类、给药途径、关联性评价及转归等方面进行统计分析。结果:223例ADR报告涉及71种药品。其中,抗菌药物有32个品种,ADR 148例,占总例数的66.37%;其次为中药注射剂,有10个品种,ADR 28例,占12.56%。引起皮肤及附件损害的ADR最多(148例),占总例数的66.37%;其次为消化系统反应(37例),占总例数的16.59%。小于9岁的患者发生ADR的比例最高(105例,占47.09%);其次为大于60岁的老年患者(29例,占13.01%)。结论:在婴幼儿及老年患者用药过程中应密切观察其不良反应,合理使用抗菌药物和中药注射剂,加强ADR监测,促进临床合理用药。
Objective：To understand the adverse drug reactions （ADR） damage and brings to the patient, and to explore the pre- vention measures analysis of its causes. Methods：In our hospital from 2012 January to December ADR report 223 cases, age of pa- tients, ADR, drug type, route of administration, relevance evaluation and outcome in areas such as statistics, analysis. Results： ADR reports of 223 cases involving 71 kinds of drugs. Among them, there are 32 varieties of antibacterial drugs, 148 cases of ADR, 66. 37% of the total number of cases; followed by the injection of traditional Chinese medicine, there are 10 varieties, ADR 28 ca- ses, accounting for 12.56 %. Cause damage to the skin and accessories in the expression of ADR up to ADR （148 cases）, 66.370% of the total number of cases; followed by the digestive system reactions （37 cases）, 16.59 % of the total number of cases. The highest proportion of less than ADR occurred in 9 patients （105 cases, 47.09%）, followed by patients older than 60 years （29 cases, 13.01%）. Conclusion ： Infants and young children and the elderly patients should be closely observed adverse reaction during the treatment, the rational use of antimicrobial drugs and traditional Chinese medicine injections, strengthen the monitoring of ADR, promote clinical rational drug use.
出处
《亚太传统医药》
2014年第6期137-139,共3页
Asia-Pacific Traditional Medicine
关键词
药品不良反应
统计分析
合理用药
Adverse Drug Reaction
Statistical Analysis
Rational Drug Use
