摘要
目的探讨血脂及尿酸(uric acid,UA)变化与脑梗死和冠心病的关系。方法 170例心脑血管病患者,分为脑梗死组(60例)、冠心病组(59例)、脑梗死合并冠心病组(51例)。同期在作者医院体检中心的健康体检者(100例)为对照组。测定各组的总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、UA,并进行差别分析。结果脑梗死组、冠心病组、脑梗死合并冠心病组的TC、TG、LDL-C、UA水平含量均高于对照组(P<0.01),HDLC水平含量均低于对照组(P<0.01);脑梗死合并冠心病组的TC、TG、LDL-C、UA水平含量均高于冠心病组、脑梗死组(P<0.01),HDL-C水平含量均低于冠心病组、脑梗死组(P<0.01);而脑梗死组和冠心病组血脂及尿酸水平无统计学差异(P>0.05)。结论血脂及尿酸异常与脑梗死和冠心病的发生、发展密切相关,为防并发症发生治疗中应加强监测。
Objective To investigate the changes of lipid and uric acid （UA） in patients with coronary heart disease and cerebral infarction. Methods A total of 170 patients with cardiovascular disease were divided into cerebral infarction group （60 cases） , coronary heart disease group （59 cases） and cerebral infarction complicated with coronary heart disease group （51 cases）. The healthy subjects in the medical center during the same period （100 cases） were the control group. Total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL-C）, low density lipoprotein choles- terol （LDL-C）,UA were measured and compared. Results TC, TG, LDL-C, UA levels were higher, and HDL-C levels were lower in three patient groups than those in the control group （P〈0. 01）. The complicated group had higher TC,TG, LDL-C,UA levels and lower HDL-C level than the other patient groups （P〈0. 01）. There was no significant difference in blood lipid and uric acid levels in cerebral infarction and coronary heart disease groups （P〉0. 05）. Conclusion The ab- normal blood lipids and uric acid is closely related with the occurrence and development of coronary heart disease and cere- bral infarction, which should be monitored for the treatment and complications prevention.
出处
《华南国防医学杂志》
CAS
2014年第2期117-119,共3页
Military Medical Journal of South China
关键词
冠心病
脑梗死
血脂
尿酸
Coronary heart disease
Infarction
Lipid
Uric acid
