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2种预冲方法对无肝素血液透析患者效果的比较 被引量:12

The comparison of two different pre-flushing methods in heparin free patients with hemodialysis
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摘要 目的探讨2种无肝素血液透析(HFHD)预冲方法对透析器、透析管路凝血以及生理盐水冲洗管路次数的影响,以寻求合理的预冲方法。方法选择30名(120例次)无肝素血液透析患者随机分为A组、B组,每组15名患者各60例次。A组采用传统方法冲洗管路,B组采用改良后方法,即生理盐水500 mL+肝素100 mg排尽管路空气后密闭式循环超滤30 min。2组透析机温度均调为38.5℃,连接患者前均用生理盐水冲洗管路,血液透析期间每1 h用生理盐水冲洗透析管路1次,并根据管路凝血情况增加冲洗次数。结果 2种预冲方法透析后患者透析器、透析管路凝血以及生理盐水冲洗管路次数的差异均具有统计学意义(P<0.05)。结论改良后的方法能明显减少血液透析中透析器、透析管路凝血现象和生理盐水冲洗次数。 Objective To explore the effect of two different pre-flushing methods on dialyz- er, blood clotting of pipelines and the number of flushing by physiological saline to seek reasonable pre-flushing method. Methods A total of 30 heparin free patients with hemodialysis were equally divided into A group and B group. The traditional method was used in the group A and the modified method was used in the group B. The air in the pipeline was evacuated by 500 mL physiological saline and 100 mg heparin in the group B and they were circulated in the closed pipeline. The tem- perature of the dialyzer of two groups was 38.5℃ and the pipeline of dialyzer was all washed with physiological saline before the connection with patients. During hemodialysis, the pipeline of dialyz- er was flushed every 1 hour and the times of flushing were added according to the condition of blood clotting. Results The differences was statistically significant in the comparion of blood clotting of dialyzer and pipeline, and the number of flushing by physiological saline between the two methods (P 〈 0.05). Conclusin The modified method can significantly reduce blood clotting of dialyzer and pipeline and decrease the number of flushing by physiological saline.
作者 胡春红
出处 《实用临床医药杂志》 CAS 2014年第4期49-50,共2页 Journal of Clinical Medicine in Practice
关键词 预冲 肝素 血液透析 pre-flushing heparin hemodialysis
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