摘要
目的 观察利咽糖浆对放射性食管炎的预防作用.方法 将90例需行放射治疗的胸部肿瘤患者随机分为3组,每组30例.治疗组从放疗当日开始口服利咽糖浆,每日50 mL,直至放疗结束.对照1组从放疗当日开始口服20％甘露醇250 mL加地塞米松20 mg加庆大霉素60万U,每日50 mL,分成4～6次口服,直至放疗结束.对照2组从放疗当日予复合维生素B液（0.9％氯化钠注射液250 mL加维生素B片5片）口服,每日50 mL,分成4～6次口服,直至放疗结束.结果 放疗后3组患者均发生了不同程度的急性放射性食管炎,治疗组及对照1组放射性食管炎的严重程度较对照2组轻微,且发生时间较对照2组明显推后,持续时间较对照2组明显缩短,治疗组与对照1组比较其放射性食管炎的严重程度、发生时间、持续时间差别不大.结论 口服利咽糖浆对放射性食管炎有良好的预防及治疗作用,可减轻放射性食管炎的严重程度,推迟其发生时间,缩短其持续时间,与对照1组有同等治疗效果.
Objective：To observe the preventive effect of Liyan syrups on radioesophagitis.Methods：90 cases with breast cancer were randomized into 3 groups,30 patients in each group.The treatment group was given Liyan syrup,50 mL daily,from the first day until the end of radiotherapy.The control group 1 was given 20％ mannitol 250ml plus dexamethasone 20 mg and gentamicin 600000 U 50 ml daily from the beginning of radiotherapy.The medicines were divided into 4～6 times one day to be orally taken until the end of radiotherapy.The control group was given compound vitamin B solution （0.9％ sodium chloride 250 mL plus vitamin B tablets,5 tablets daily） orally,50 mL,divided into 4～6 times one day,until the end of radiotherapy.Results：After radiotherapy,patients in 3 groups developed acute radioesophagitis of different degrees.Severity of treatment group and control group 1 was minor than that of control group 2.Compared with control group,the occurrence of time was significantly delayed and the duration was shortened in treatment group and in control group 1.Radioesophagitis severity,occurrence time,and duration time had no differences between treatment group and control group 1.Conclusion：Liyan syrups have preventive and therapeutic effect on radioesophagitis and can reduce severity of radioesophagitis,delay occurrence time,and shorten duration.The control group 1 shares the same treatment effect.
出处
《中国中医急症》
2014年第3期430-431,共2页
Journal of Emergency in Traditional Chinese Medicine
基金
重庆市卫生局科研课题(2011-2-3)
