摘要
目的：了解武当山旅游经济特区医院药品不良反应（ADR）发生的情况及一般规律,为临床合理用药提供参考.方法：对我院2011年1月-2012年12月上报的143例ADR报告,按患者性别、年龄、药物类别、累及器官和（或）系统及临床表现进行统计、分析.结果：143例ADR报告中,男性（54例,占37.76％）少于女性（89例,占62.24％）;在年龄分布方面,41～60岁患者较多（58例）,占总病例数的40.56％;ADR的给药途径以静脉给药为主（113例）,占总病例数的79.02％;由抗菌药物导致的ADR为最多（62例）,占总病例数的43.36％;ADR的表现以皮肤及其附件的损害最为常见（67例）,占总病例数的46.85％.结论：引起ADR的原因很多,医务人员应高度重视,开展全方位的监测,提高ADR的预防与救治能力,减少ADR发生.
OBJECTIVE：To investigate the occurrence of the adverse drug reactions（ADRs） and its regularity in Wudang Mountain Tourism Special Economic Zone Hospital in order to provide reference for clinical rational use of drugs.METHODS：A total of 143 ADR cases reported by our hospital from Jan.2011 to Dec.2012 were analyzed statistically in respect of patients＇ age and sex,drug types,organs and （or） systems involved and clinical manifestation.RESULTS：The total 143 ADR cases were more often seen in males than in females [54 cases （37.76％） vs.89 cases （62.24％）],in patients aged from 41 to 60 （58 cases,40.56％）,in patients administered with drugs intravenously （113 cases,79.02％）,and the ADRs were induced more often by anti-infection drugs （41.96％） and manifested chiefly as lesions of skin and its appendants （67 cases,46.85％）.CONCLUSION：The occurrence of ADR is associated with many factors,and it is important for medical staff to attach great importance by carrying out ADR monitoring so as to enhance the ability to prevent and treat ADRs and reduce the incidence of ADRs.
出处
《中国医院用药评价与分析》
2014年第2期157-159,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
分析
合理用药
Adverse drug reaction（ADR）
Analysis
Rational use of drugs
