摘要
[目的]观察止咳平喘中药联合西药治疗支气管哮喘疗效。[方法]使用随机平行对照方法,将80例住院患者按随机数字表方法随机分为两组。对照组40例复方甲氧那明,2粒/次,3次/d,餐后服用;沙美特罗替卡松粉剂吸入,1吸/次,2次/d;呼吸道感染抗生素治疗。治疗组40例,止咳平喘中药(炙麻黄、苏子各12g,枳壳、地龙、黄芩、莱菔子、桑白皮、白芥子各10g,杏仁15g,生甘草6g,),每剂煎2次,每次加水500mL,取汁200mL,共400mL,1剂/d,分早晚温服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、肺功能(1s用力肺活量-FEV1-、最大呼气流速-PEF、FEV1/FVC、)嗜酸性粒细胞(EOS)、白细胞介素8(IL-8)、肿瘤坏死因子(TNF-α)、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组临床控制10例,显效17例,好转11,无效2例,总有效率95.00%。对照临床控制6例,显效11例,好转14例,无效9例,总有效率77.50%。治疗组疗效优于对照组(P<0.05,P<0.01)。生化指标改善治疗组优于对照组(P<0.05,P<0.01)。[结论]止咳平喘中药治疗支气管哮喘,疗效满意,无副作用,值得推广。
[ Objective ] To observe the clinical curative effect of traditional Chinese medicine of relieving cough and asthma combined with western medicine in the treatment of bronchial asthma. [ Methods ] Retrospectively analysed 80 cases with bronchial asthma, and divided the patients into two groups by random number table method, 40 cases in the control group took compound methoxyphenamine, 2 capsules each time, 3 times a day, after meal ; inhaled salmeterol and fluticasone propionate powder, 1 suction each time, 2 times a day ; and respiratory tract infections was treated with antibiotics , and 40 eases in the treatment group were treated with traditional Chinese medicine for relieving cough and asthma, ephedra 12g, suzi 12g, fructus aurantii 10g, eatthworm 10g, scutellaria 10g, radish seed 10g, mulberry bark 10g, baijiezi 10g, almond 15g, licorice root 6g, prepared by Decoction Room of Zhuhai People＇s Hospital, and decocted each agent for 2 times with water 500mlto 200ml, ldoses/d, took it in morning and evening; western medicine was same with the control group. Treated for 7d as 1 course, compared the symptom and signs before and after treatment, lung function, forced vital capacity for 1 minute （ FEV1 ）, peak expiratory flow （ PEF ） , FEV1/FVC, eosinophilic granulocyte count （ EOS ） in serum, interleukin 8 （ IL-8 ）, tumor necrosis factor alpha （ TNF-α ） levels, adverse reaction. Treated for3 courses continuously, then judged curative effect. [ Results ] 10 cases in the treatment group were controlled.17 cases were effective. 2 cases were no effective, the total effective rate in the treatment group was 95.00%; 6 cases in the treatment group were controlled.11 cases were effective.14 cases were better than before. 9 cases were no effective, the total effective rate in the treatment group was 77.50% ; The curative effect of the treatment group was better than that of the control group （P〈0.05, P〈0.01 ）, the biochemical criterion of the treatment group was better than that of the control
出处
《实用中医内科杂志》
2013年第9期51-54,共4页
Journal of Practical Traditional Chinese Internal Medicine
