摘要
目的探讨心肌肌钙蛋白I(cTnI)、C-反应蛋白(CRP)和B型钠尿肽(BNP)联合检测对缺血型心力衰竭(心衰)诊断和预后的判断价值。方法收集并测定98例缺血型心衰的不同心功能分级患者及95例冠心病无心衰患者血清cTnI、CRP和血浆BNP等指标,并进行比较,随访观察患者近期心脏事件再发生情况。结果心衰患者不同心功能分级组血清cTnI、CRP和血浆BNP水平与无心衰组之间差异均有统计学意义,且心功能越差,其浓度越高(P均<0.05)。发生心脏事件组患者出院时血清cTnI、CRP和血浆BNP浓度明显高于未发生心脏事件组(P均<0.05)。结论血清cTnI、CRP和血浆BNP在心衰患者中明显升高,三者联合检测对心衰患者临床诊断和预后判断有重要意义。
Objective To explore the diagnostic and prognostic values of combined measurements of cardiac troponin I（cTnI）, C reactive protein（CRP）and B-type natriuretic peptide（BNP）in patients with ischemia heart fail-ure.Methods The serum cTnI, CRP and blood plasma BNP in 98 cases ischemic heart failure patients with different cardiac function classification and 95 coronary heart disease without heart failure patients , and a follow-up observation of the recurrence of recent cardiac events was performed .Results The levels of serum cTnI , CRP and blood plasma BNP between heart failure patients with different cardiac function grading and the control group were compared , and the differences were statistically significant .The worse the heart function was , the higher the concentration was （ P＆lt;0.05）.Serum cTnI, CRP and plasma BNP concentrations at hospital discharge in the cardiac events group were markedly higher than those in the non-cardiac events group （ P＆lt;0.05 ） .Conclusion Serum cTnI , CRP and plasma BNP concentrations in patients with congestive heart failure obviously increase , and the combined measurements of three indexes have important significance in clinical diagnosis and prognostic evaluation for heart failure .
出处
《中国临床新医学》
2014年第2期130-133,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
高敏C反应蛋白
B型钠尿肽
心力衰竭
预后判断
肌钙蛋白I
Troponin I
C reactive protein
B-type natriuretic peptide
Heart failure
Prognosis e-valuation
