摘要
目的观察瑞芬太尼对老年高血压病人全麻诱导后气管插管时的血流动力学的影响。方法择期拟行胃肠肿瘤切除手术的老年高血压患者50例，年龄65—75岁。随机分为瑞芬太尼组（R组）和芬太尼组（F组），每组25例。分别记录两组麻醉诱导前（T0）、诱导后（T1）、气管插管即刻（T2）及插管后1min（T3）、3min（T4）、5min（T5）的MAP和HR。结果与T0时比较，两组T1时MAP明显下降，HR明显减慢（P〈0．05），T2、T3时F组MAP明显升高，HR明显增快（P〉0．05）；T2、T3时R组MAP明显低于、HR明显慢于F组（P〈0．05）；T4、T5时R组MAP明显高于F组（P〈0．05）HR比较差异无统计学意义（P〉0．05）。结论瑞芬太尼适用于老年高血压病人的麻醉诱导，能有效地抑制气管插管引起的心血管反应，更好地维持血流动力学稳定。
Objective To observe the efficacy of remifentanil infusion on intratracheal tube hemodynamics in elderly patients with elevated blood pressure . Methods Fifty ASA Ⅰ orⅡ patients （Mallampati Ⅰ or Ⅱ）,aged 65-75 yr, scheduled for elective rad- ical mastectomy under general anesthesia,were randomized into 2 groups （n=25 each）： the remifentanil group （group R） and fen- tanyl group （group F）. Heart rate and mean artery pressure were recorded before induction （T0）, after induction （T1）, at the same time, intubated （T2）, at lmin after intubation （T3）, 3min （T4）, 5min （T5）. Results Mean artery pressure in two groups of T1 was significantly lower than that TO, Heart rate was significantly slower （P〈0.05）; Mean artery pressure in two groups of F （ T2 and T3） was significantly higher, Heart rate was significantly faster （P〉0.05）; Mean artery pressure in two groups of R （ T2 and T3） was significantly lower than group F, Heart rate was significantly slower than group F （P〈0.05）; Mean artery pressure in two groups of R （ T4 and T5） was significantly higher than group F （P〈0.05）; No statistically significant difference in HR （P〉0.05）.Conclusion Induction of anesthesia with remifentanil for elderly patients with hypertension, cardiovascular reaction can effectively inhibit tra- cheal intubation, to better maintain the stability of hemodynamics.
出处
《中国卫生产业》
2014年第7期25-26,共2页
China Health Industry
关键词
瑞芬太尼
老年患者
高血压
气管插管
血流动力学
Remifentanil
Elderly patients
Elevated blood pressure
Intratracheal tube
Hemodynamics
