摘要
炎症性肠病(inflammatory bowel disease,IBD)是一组反复发作的慢性炎症性肠道疾病,主要包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD)。其确切的发病机制目前尚不明确,本文主要对遗传因素、免疫因素、环境因素、内质网应激和肠道微生物这五个方面在IBD中的新观点作一概述。
Inflammatory bowel disease (IBD) is a group of recurrent chronic inflammatory bowel disease, which includes UC and CD. The exact pathogenesis is unclear. This paper reviews new progress in IBD about genetic factors, immune factors, environmental factors, endoplasmic reticulum stress and intestinal flora.
出处
《胃肠病学和肝病学杂志》
CAS
2014年第2期124-126,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
炎症性肠病
易感基因
内质网应激
肠道菌群
Inflammatory bowel disease
Susceptibility genes
Endoplasmic reticulum stress
Intestinal flora