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血管紧张素抑制剂对腹膜透析患者生存率及技术生存率的影响

Effects of Angiotensin Inhibitor on Survival Rate and Technique Survival Rate in Continuous Ambulatory Peritoneal Dialysis Patients
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摘要 目的:腹膜透析患者使用血管紧张素抑制剂与否对患者生存率和技术生存率的影响。方法:回顾性分析2008年1月-2013年1月在笔者所在医院规律随访的维持性腹膜透析患者,分为使用血管紧张素抑制剂组(ACEI/ARB组)148例,未使用(非ACEI/ARB组)100例,对比有无使用血管紧张素抑制剂对生存率的影响。结果:ACEI/ARB组患者存活率87.2%,非ACEI/ARB组56.0%(P<0.05),两组对比生存曲线显示明显差异;且ACEI/ARB组技术生存率也明显好于非ACEI/ARB组(77.0%vs 46.0%,P<0.05)。结论:长期使用血管紧张素抑制剂可改善腹膜透析患者生存率及技术生存率。 Objective:The present study was to investigate the effect of angiotensin inhibitor on survival rate in continuous ambulatory peritoneal dialysis patients.Method:To retrospective study in patients who had undergone continuous ambulatory peritoneal dialysis(CAPD) from January 2008 to January 2013. Patients were divided into two groups,ACEI/ARB group 148 cases and non-ACEI/ARB group 100 cases,and survival rate was calculated.Result:There was significant statistical difference in patients survival rates between ACEI/ARB group and non-ACEI/ARB group(87.2%vs 56.0%,P〈0.05).Meanwhile patients in ACEI/ARB group had better technique survival rate compared with patients in non-ACEI/ARB group(77.0%vs 46.0%,P〈0.05).Conclusion:Long time using AECI/ARB is effective for patient and technique survival rates.
出处 《中外医学研究》 2014年第5期18-19,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 血管紧张素抑制剂 腹膜透析 生存率 Angiotensin inhibitor Peritoneal dialysis Survival rate
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参考文献8

  • 1Ondocin P T, Narsipur S S.Influence of angiotensin converting enzyme inhibitor treatment on cardiac autonomic modulation in patients receiving haemodialysis[J].Nephrology, 2006, 11(6): 497-501. 被引量:1
  • 2钟慧,沙朝晖,崔天蕾,邱红渝,刘芳,秦伟,付平.依贝沙坦对维持性腹膜透析患者残存肾功能的保护作用[J].中华肾脏病杂志,2007,23(7):413-416. 被引量:6
  • 3孙晶,张虹,于克洲,王群,王荣.肾素血管紧张素系统抑制剂对长期腹膜透析患者腹膜纤维化和残余肾功能的作用[J].中国血液净化,2010,9(3):152-155. 被引量:10
  • 4Taner B, Unsal I A, Koc I Y.The effects of angiotensin-converting enzyme inhibitors on peritoneal protein loss and solute transport in peritoneal dialysis patients[J].Clinical, 2012, 67(8): 877-883. 被引量:1
  • 5Kolesnyk I, Noordzij M, Dekker F W, et al.A positive effect of AII inhibitors on peritoneal membrane function in long-term PD patients[J]. Nephrol Dial Transplant, 2009, 24(1): 272-277. 被引量:1
  • 6Fang W, Oreopoulos D G, Bargman J M.Use of ACE inhibitors or angiotensin receptor blockers and survival in patients on peritoneal dialysis[J].Nephrol Dial Transplant, 2008, 23(11): 3704-3710. 被引量:1
  • 7Devrim B, Pinar C, Savas S, et al.The effects of enin- angiotensin system inhibition on regression of encapsulating peritoneal sclerosis[J].Peritoneal Dialysis International, 2008, 28(5): S38-S42. 被引量:1
  • 8Denise E S, Inna K, Mario R K, et al.Use of angiotensin Ⅱ inhibitors in patients that develop encapsuiating peritoneal sclerosis[J].Peritoneal Dialysis International, 2010, 6(30): 656-659. 被引量:1

二级参考文献15

  • 1Long CHEN Bi-cheng LIE Xiao-liang ZHANG Jian-dong ZHANG Hong LIU Min-xia LI.Influence of connective tissue growth factor antisense oligonucleotide on angiotensin II-induced epithelial mesenchymal transition in HK2 cells[J].Acta Pharmacologica Sinica,2006,27(8):1029-1036. 被引量:21
  • 2Li PK, Chow KM, Wong TY, et al. Effects of an angiotensin-converting enzyme inhibitor on residual renal function in patients receiving peritoneal dialysis. A randomized, controlled study. Ann Intern Med, 2003, 139: 105-112. 被引量:1
  • 3Phakdeekitcharoen B, Leelasa-nguan P. Effects of an ACE inhibitor or angiotensin receptor blocker on potassium in CAPD patients. Am J Kidney Dis, 2004, 44: 738-746. 被引量:1
  • 4Bargman JM, Thorpe KE, Churchill DN. Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study. J Am Soc Nephrol, 2001, 12: 2158-2162. 被引量:1
  • 5Wang AY, Woo J, Lain CW, et al. Associations of serum fetuin-A with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients. Nephrol Dial Transplant, 2005, 20: 1676-1685. 被引量:1
  • 6Levin A, Thompson CR, Ethier J, et al. Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin. Am J Kidney Dis, 1999, 34: 125-134. 被引量:1
  • 7Winchester JF, Rotellar C, Goggins M, et al. Calcium and phosphate balance in dialysis patients. Kidney Int Suppl, 1993, 41: S174-S178. 被引量:1
  • 8Wang AY, Woo J, Wang M, et al. Important differentiation of factors that predict outcome in peritoneal dialysis patients with different degrees of residual renal function. Nephrol Dial Transplant, 2005, 20: 396-403. 被引量:1
  • 9Fogo AB. The role of angiotensin Ⅱ and plasminogen activator inhibitor-1 in progressive glomerulosclerosis. Am J Kidney Dis, 2000, 35: 179-188. 被引量:1
  • 10Kagami S, Border WA, Miller DE, et al. Angiotensin Ⅱ stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest, 1994, 93: 2431- 2437. 被引量:1

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