摘要
目的观察应用10天序贯疗法在HP感染性浅表型胃炎患者中的临床效果,根据其HP根除率,对患者采取疗效较好的治疗方法。方法选择在我院确诊的浅表型胃炎且伴有HP感染患者共计128例。将患者随机分为实验组和对照组。实验组行10天序贯疗法,对照组行三联药物疗法。两组患者在停药后进行胃镜检查及14C的呼吸试验,并检测HP根除率。结果实验组治疗有效率为96.9%,对照组为71.9%。实验组14C的呼吸试验结果有95.3%患者转阴性明显高于对照组的70.3%。实验组HP转阴率为98.4%,对照组HP转阴率为73.4%。两组比较有显著性差异,P<0.05。结论临床治疗过程中对HP感染性浅表型胃炎患者采取10天序贯疗法具有显著疗效,同时对HP根除的效果也非常明显。
Objective To observe the clinical efficacy and HP eradication rate of 10-day sequential therapy for HP infection superficial gastritis ,looking for better treatment for patients according to the eradication rate. Methods 128 patients diagnosed with superficial gastritis and infected by HP in our hospital were randomly divided into experimental group and control group. The experimental group accepted 10-day sequential therapy and the control group was treated with triple drugs. The two groups were given gastroscope examination after drug withdrawal, respiratory experiment of 14C and detected HP eradication rate. Results Effective rate of experimental group （96.9%） was higher than that of control group （71.9%）. In results respiratory experiment of 14C ,patients became negative of experimental group （95.3%） was significantly higher than that of control group （70.3%） ,HP became-negative rate of experimental group was 98.4% and that of control group was 73.4%. Differences of two groups were statistically significant（P〈0.05）. Conclusion Applying 10-day sequential therapy in superficial gastritis patients who are infected with HP has significant efficacy and effect on HP eradication rate significantly.
出处
《中国现代医药杂志》
2014年第2期57-59,共3页
Modern Medicine Journal of China
关键词
10天序贯疗法
浅表型胃炎
HP感染
HP根除率
10-day sequential therapy Superficial gastritis HP infection HP eradication rate
