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上消化道疾病与幽门螺杆菌感染的关系研究 被引量:16

Correlation between diseases of upper digestive tract and Helicobacter pylori infections
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摘要 目的探讨上消化道疾病与幽门螺杆菌(Hp)感染的相关性,为正确诊断和有效治疗上消化道疾病提供科学的实验室依据。方法回顾性查阅和分析1187例上消化道疾病患者的病历资料,重点统计患者年龄、临床诊断和Hp检查结果。结果 1187例上消化道疾病患者中,Hp检查结果阳性的607例,阳性率为51.1%,各年龄组患者阳性率差异无统计学意义;临床常见的上消化道疾病中,以十二指肠溃疡Hp感染率最高,达到100.0%,以慢性浅表性胃炎Hp感染率最低,为40.4%,其他上消化道疾病Hp感染率在44.4%~98.4%。结论上消化道疾病与Hp感染有着密切的关系,检测Hp对于诊断、治疗上消化道疾病具有重要的临床意义。 OBJECTIVE To explore the correlation between the diseases of upper digestive tract and the Helicobacter pylori (Hp) infections so as to provide scientific experimental evidence for diagnosis and treatment of diseases of upper digestive tract. METHODS The medical records of 1187 cases of patients with upper digestive tract diseases were retrospective reviewed and analyzed, then the statistical analysis of the age was performed, and the results of the clinical diagnosis and Hp examination were observed. RESULTS Of totally 1187 cases of diseases of upper digestive tract who underwent the test of Hp, 607 cases were positive with the positive rate of 51. 1%, the difference in the positive rate between the various age groups was not sisnit cant. Among the cases with common diseases of upper digestive tract, the incidence rate of Hp infection was the highest in the cases of duodenal ulcer, reaching up to 100.0%, while it was the lowest (40.4%) in the patients with chronic superficial gastritis, and the incidence rate of Hp infection varied between 44. 4% and 98. 4% among the cases of other diseases of upper digestive tract. CONCLUSION There is close correlation between the diseases of upper digestive tract and the Hp infection. The detection of Hp has important clinical significance in the diagnosis and treatment of diseases of upper digestive tract.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2013年第21期5181-5182,共2页 Chinese Journal of Nosocomiology
基金 湖北省科技厅自然科学基金(2012FFC120)
关键词 幽门螺杆菌 感染 上消化道疾病 Helicobacter pylori Infection Disease of upper digestive tract
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