摘要
目的探讨缺血性脑血管病(Ischemic cerebrovascular disease,ICVD)患者血脂、同型半胱氨酸(Homocysteine,Hcy)水平及其临床价值。方法选择缺血性脑血管病患者80例(其中短暂脑缺血发作患者38例,脑梗死患者42例)作为研究组,本院健康体检者40例作为对照组,检测血清Hcy、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平,并与对照组进行比较,分析其相关性。结果缺血性脑血管病患者组血Hcy、TG明显高于对照组(P<0.01),血清TC、HDL-C、LDL-C与对照组比较,差异无统计学意义(P>0.05);且Hcy水平与血脂水平无明显相关性。结论高Hcy、高TG水平是诱发缺血性脑血管病发作的危险因素,定期监测Hcy、TG水平对ICVD的预防及疾病诊断及预后判断有重要临床意义。
Objective To investigate the levels of lipids and serum Hcy, as well as the clinical values in patients with ischemic cerebrovascular disease（ICVD）. Methods Eighty patients with ischemic cerebrovascular disease （including 38 patients with transient ischemic attacks and 42 patients with cerebral infarction）as the study group, and 40 cases of healthy persons as control group were involved to detect the levels of serum Hcy, triacylglycerol（ TG）, total cholesterol （TC）, high density lipoprotein cholesterol（ HDL- C） and low density lipoprotein cholesterol（ LDL- C）, and the detection results were compared between the two groups to analyze the correlation between Hcy and other indicators. Results The levels of Hcy, TG in ICVD patients were significantly higher than the control group（P 〈 0.01 ）. While there was no statistical difference in levels of HDL - C, TC and LI）L- C between ICVD group and the control group（P 〉0.05） ; The Hcy levels had no significant correlation with serum lipid levels. Conclusion High levels of Hcy and TG are risk factors of ischemic cerebrovascular disease onset, so regular monitoring of Hcy and TG has important clinical significance for prevention, diagnosis and prognosis of ICVD.
出处
《中国卫生检验杂志》
北大核心
2014年第3期390-391,共2页
Chinese Journal of Health Laboratory Technology
关键词
缺血性脑血管病
同型半胱氨酸
血脂
Ischemic cerebrovascular disease
Homocysteine
Blood lipid
