摘要
建立了兽药在不同环境介质中的暴露浓度预测方法,选择我国养殖业常用的3种典型兽药抗生素磺胺二甲嘧啶（SDM）、土霉素（OTC）和恩诺沙星（ENF）,对其环境暴露评估进行研究.结果显示,粪便中SDM的土壤预测暴露水平（PEC）为53.07～735.07 mg·kg-1,OTC的PEC为13.30～160.51 mg·kg-1,ENF的PEC为1.60～40.35 mg·kg-1;土壤中SDM的最大PEC为534.84～ 13 820.24 μg·kg-1,OTC的最大PEC为172.66～3 054.71μg·kg-1,ENF的最大PEC为67.61～2 484.71 μg·kg-1;地表水中SDM的PEC为134.27～3 469.62 μg ·L-1,OTC的PEC为0.12～2.18 μg· L-1,ENF的PEC为0.02～0.87 μg·L-1.通过比较PEC与相关文献的实际检测结果,初步探索了兽药环境暴露预测模型在我国兽药环境暴露评估中的适用性.
A method was established to predict environmental exposure level of veterinary drugs, and used in the study on environmental exposure assessment of sulfadimidine （ SDM）, oxytetracycline （ OTC ） and enrofloxacin （ENF） in China, which are the 3 most frequently used types of veterinary antibiotics in China. In animal dung, SDM ranged between 53.07- 735.07 mg ·kg · in PEC, OTC between 13.30-160. 51 mg· kg-1 and ENF between 1.60-40. 35 mg·kg-1 ; while in soil, the highest PEC did between 534. 84-13 820. 24 μg ·kg-1 with SDM, between 172. 66-3 054. 71μg · kg-l with OTC and between 67.61-2 484. 71μg ·kg-1 with ENF; and in water it did between 134. 27-3 469. 62 μg ·L-l with SDM, between 0. 12-2. 18 μg · L-1 with OTC and between 0. 02-0. 87μg · L-1 with ENF. By comparing PEC with the measured data reported in literatures, primary exploration was done to evaluate applicability of the veterinary drug environ- mental exposure prediction model to the environmental exposure assessment of veterinary drugs in China.
出处
《生态与农村环境学报》
CAS
CSCD
北大核心
2014年第1期77-83,共7页
Journal of Ecology and Rural Environment
基金
环保公益性行业科研专项(201109038
201309031)
关键词
兽药
磺胺二甲嘧啶
土霉素
恩诺沙星
环境暴露评估
veterinary drug
sulfadimidine
oxytetracycline
enrofloxacin
environmental exposure assessment
