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急性脑梗死患者C反应蛋白的测定及临床意义 被引量:1

Determination of protein C and its clinical significance in patients with acute cerebral infarction
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摘要 目的研究C反应蛋白测定在急性脑梗死(ACI)患者病情及预后预测中的意义。方法选取我院2011-01—2012-01收治的急性脑梗死患者40例为ACI组,选取同期体检健康者40例为对照。入院后1d、7d和14d分别检测2组C反应蛋白(CRP),并在治疗前后对ACI组进行神经功能缺损评分,对预后进行评价。结果 ACI组在各个时间点CRP水平均高于对照组,差异有统计学意义(P<0.05);且ACI组中轻、中、重型患者预后不良发生率差异有统计学意义(P<0.05)。结论急性脑梗死导致CRP水平高于健康者,且CRP水平与脑梗死严重程度呈正相关;CRP过高会导致预后不良,应作为急性脑梗死重要诊疗指标。 Objective To study the significance of determination of C-reactive protein in patients with acute cerebral infarction (ACI) for the prediction of condition and prognosis. Methods Forty patients with acute cerebral infarction in our hospital from January 2011 to January 2012 were received as the ACI group, and forty healthy people were selected as controls at the same period. After admission of 1 d, 7 d and 14 d, C reactive protein (CRP) of the two groups were detected respectively, and the neurological function of ACI group was compared before and after treatment. The prognosis was evaluated. Results At each time point, the level of CRP in ACI group was higher than control group, the difference was statistically significant (P~ 0.05) ; in the ACI group, the incidence of poor prognosis of mild, moderate and severe patients gradually increased, the differ ence was statistically significant (P〈~0.05). Conclusion Acute cerebral infarction may lead to CRP levels above health and is positive correlated to CRP levels; high CRP can result in a poor prognosis. CRP should he used as an important indicator for acute cerebral infarction.
出处 《中国实用神经疾病杂志》 2014年第3期52-53,共2页 Chinese Journal of Practical Nervous Diseases
关键词 急性脑梗死 C反应蛋白 检测意义 Acute cerebral infarction C reactive protein Detection significance
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