摘要
目的：评价心外膜脂肪（EAT）厚度与冠状动脉（冠脉埔变严重程度的关系。方法：连续入选169例急性心肌梗死（AMI）患者．分别进行冠脉造影检查和经胸超声心动图检查，采集右心室游离壁EAT厚度。冠脉严重程度采用SYNTAX评分，根据冠脉造影结果进行SYNTAX评分，再依据评分结果将169例患者分为高评分组（评分≥33分，n=67）和低积分组（评分〈33分，n=02）。通过Person相关分析确定有心室游离壁EAT厚度与冠脉病变严重程度的关系，通过多元回归分析确定冠脉病变的危险因素。结果：高积分组冠脉三支病变患者比例（83．6％）高于低积分组（30．4％），高积分组有心室游离壁EAT厚度（6．4±0．8）mm高于低积分组（4．8±0．7）mm，差异均有统计学意义（P〈0．05）。有心室游离壁EAT厚度与SYNTAX评分呈显著正相关（r=0．785，P〈0．01）。多因素回归分析显示，右心室游离壁EAT厚度与SYNTAX评分较高（评分≥33分）俘在独直相关性（OR=5．17，95％CI：3．10～8．63；P〈0．01）。结论：心肌梗死患者EAT与SYNTAX评分具有显著相关性。EAT与SYNTAX评分存在独赢的关联。
Objective： To evaluate the relationship between the thickness of epicardial adipose tissue （EAT） with the severity of coronary artery lesions. Methods： A total of 169 consecutive patients with coronary angiography diagnosed acute myocardial infarction （AMI） were summarized and echocardiography was used to examine the thickness of right ventricular EAT. The patients were divided into 2 groups according to SYNTAX score, High score （ ≥ 33） group, n=67 and Low score （〈33） group, n=102. The relationship between the thickness of right ventricular EAT with the severity of coronary artery lesions and the risk factors were measured by Pearson correlation analysis and multivariate regression analysis respectively. Results： The patients with 3-branch lesions and the thickness of EAT in High score group are both higher than those in Low score group （83.6% vs 30.4%） and （6.4±0.8 vs 4.8±0.7） mm, both P〈0.05. Pearson correlation analysis indicates that EAT is positively related to SYNTAX score （r=0.785, P〈0.01）. Multivariate regression analysis presents that the thickness of right ventricular EAT is independent to related to high SYNTAX score （〉 33）, （OR=5.17, 95%CI 3.10-8.63, P〈0.01 ）. Conclusion： The thickness of EAT is obviously and independently related to SYNTAX score in AMI patients .
出处
《中国循环杂志》
CSCD
北大核心
2014年第2期99-102,共4页
Chinese Circulation Journal
