摘要
目的 :观察丹参注射液对实验性输卵管炎性阻塞家兔红细胞膜脂流动性的影响。方法 :制备输卵管炎性阻塞的家兔模型 ,iv给予丹参注射液 1.5 g/kg,3g/kg,1次 /d,连续 (43.3± 4.89) d,测试对红细胞膜脂流动性的影响。结果 :丹参注射液组与模型对照比较可使输卵管炎性阻塞家兔红细胞膜脂的荧光偏振度减小 ,使红细胞膜脂区微粘度明显降低。结论 :丹参注射液对炎症时的兔红细胞膜有明显的保护作用。
Objective:To observe the effect of Danshen injection on lipid fluidity of erythrocyte membrane in the rabbits of fallopian tubal inflammatory obstruction.Methods:To prepare models of fallopian tubal inflammatory obstruction in rabbits.Danshen injection was iv at the dose of 1.5 g/kg and 3 g/kg one time a day and continued (43.30±4.89)d,then the influence of Danshen injection on lipid fluidity of erythrocyte membrane measured.Results:The groups of Danshen injection could reduce the fluorescence polarization of erythrocyte membrane in the rabbits of fallopian tubal inflammatory obstruction and significantly decrease the lipid microviscosity of erythrocyte membrane comparing to the group of model contrast.Conclusion:Danshen injection could protect the erythrocyte membrane of rabbits in inflammation.
出处
《时珍国医国药》
CAS
CSCD
2001年第2期104-105,共2页
Lishizhen Medicine and Materia Medica Research
关键词
丹参注射液
输卵管炎性阻塞
脂流动性
脂区微粘度
荧光偏振技术
中药
中医药疗法
Danshen injection
Fallopian tubal inflammatory obstruction
Membranous lipid fluidity
Fluorescence polarization
Membranous lipid microviscosity
